Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296907 | 0.81 | ALOX5 (0.62) | PARP1ALOX5PTPN1ALDH1A1HSD17B10 | |
| SCHEMBL27037276 | 0.78 | ALDH1A1 (0.41) | DRD3ALOX5PTPN1ALDH1A1HSD17B10 | |
| SCHEMBL242386 | 0.78 | DRD3 (0.47) | DRD3ALOX5PTPN1ALDH1A1HSD17B10 | |
| SCHEMBL14048659 | 0.76 | TP53 (0.45) | PARP1ALOX5PTPN1TSHRPPARG | |
| SCHEMBL3779996 | 0.76 | DRD3 (0.45) | DRD3ALOX5PTPN1ALDH1A1HSD17B10 | |
| SCHEMBL10536451 | 0.72 | ACMSD (0.56) | ALDH1A1HSD17B10ALOX15ALOX12HPGD | |
| SCHEMBL30754397 | 0.72 | PPARD (0.71) | ALOX5PTPN1TSHRCA2PPARG | |
| SCHEMBL13317169 | 0.72 | PPARD (0.71) | ALOX5PTPN1TSHRCA2PPARG | |
| SCHEMBL13074805 | 0.72 | PARP1 (0.40) | PARP1ALOX5PTPN1ALDH1A1HSD17B10 | |
| SCHEMBL10062055 | 0.71 | DRD3 (0.59) | DRD3PARP1ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275077-A1 | Methods of Obtaining Optically Active Epoxides and Vicinal Diols from Styrene Oxides | OXYRANE (UK) LIMITED (GB) | 2009-11-05 | — | — | US | disclosed |
| US-20070281339-A1 | Methods For Obtaining Optically Active Epoxides and Vicinal Diols From Styrene Oxides | OXYRANE UK LIMITED (GB) | 2007-12-06 | — | — | US | disclosed |
| EP-1756281-A2 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM STYRENE EPOXIDES USING ENANTIOSELECTIVE EPOXIDE HYDROLASES DERIVED FROM YEASTS | CSIR (ZA) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005100569-A2 | METHODS FOR THE PREPARATION OF OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM STYRENE EPOXIDES USING ENANTIOSELECTIVE EPOXIDE HYDROLASES DERIVED FROM YEASTS | CSIR (ZA) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275077-A1 | Methods of Obtaining Optically Active Epoxides and Vicinal Diols from Styrene Oxides | EPHX2, EPHX1, DERA | DRD3 2305/4885PARP1 1128/4885ALOX5 230/4885 |
| US-20070281339-A1 | Methods For Obtaining Optically Active Epoxides and Vicinal Diols From Styrene Oxides | DERA, ERG28, EPHX2 | DRD3 1687/4885PARP1 870/4885ALOX5 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.