Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884192 | 0.84 | PPARG (0.52) | ACHECA2CA1PPARGPPARD | |
| SCHEMBL29130999 | 0.83 | MAPT (0.42) | HPGDGAAMAPTALDH1A1 | |
| SCHEMBL10608754 | 0.83 | ACHE (0.54) | ACHECA2CA1PPARGPPARD | |
| SCHEMBL84033 | 0.82 | PPARG (0.53) | ACHECA2CA1PPARGPPARD | |
| SCHEMBL24509816 | 0.82 | GRM2 (0.38) | ACHECA2CA1PPARGPPARD | |
| SCHEMBL6705742 | 0.82 | CYP2D6 (0.45) | CA2CA1KMT2ACA7CA9 | |
| SCHEMBL9774382 | 0.82 | LMNA (0.44) | KMT2AALDH1A1LMNA | |
| SCHEMBL27710622 | 0.81 | PPARG (0.58) | ACHECA2CA1PPARGPPARD | |
| SCHEMBL13955907 | 0.79 | PPARG (0.55) | ACHECA2CA1PPARGPPARD | |
| SCHEMBL10865232 | 0.79 | PPARG (0.51) | ACHECA2CA1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023202559-A1 | PHENYL ACRYLIC ACID COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | 朗捷睿(苏州)生物科技有限公司 | 2023-10-26 | — | — | WO | disclosed |
| CN-111777501-B | Caffeic acid phenethyl ester derivatives, preparation method thereof, pharmaceutical compositions thereof and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |
| EP-2871187-B1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SNU R&DB FOUNDATION (KR) | 2017-09-20 | — | — | EP | disclosed |
| EP-2877470-B1 | BICYCLIC AZA-AMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V (DE) | 2017-09-13 | — | — | EP | disclosed |
| US-9745280-B2 | Compound or pharmaceutically acceptable salt thereof, and pharmaceutical composition containing same as active ingredient | SNU R&DB FOUNDATION (KR) | 2017-08-29 | — | — | US | disclosed |
| US-20160340331-A1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SNU R&DB FOUNDATION (KR) | 2016-11-24 | — | — | US | disclosed |
| US-9371322-B2 | Bicyclic aza-amides for treatment of psychiatric disorders | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-06-21 | — | — | US | disclosed |
| CN-105085450-A | Benzofuran derivatives, and preparation method and therapeutic action thereof | UNIV CHINA PHARMA | 2015-11-25 | — | — | CN | disclosed |
| US-20150183797-A1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SNU R&DB FOUNDATION (KR) | 2015-07-02 | — | — | US | disclosed |
| US-20150183786-A1 | BICYCLIC AZA-AMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-GESSELSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2015-07-02 | — | — | US | disclosed |
| CN-103848757-A | PROCESS FOR SYNTHESIS OF 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE, AND APPLICATION IN SYNTHESIS OF IVABRADINE | SERVIER LAB | 2014-06-11 | — | — | CN | disclosed |
| WO-2014015993-A1 | BICYCLIC AZA-AMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-01-30 | — | — | WO | disclosed |
| EP-2690102-A1 | Bicyclic aza-amides for treatment of psychiatric disorders | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-01-29 | — | — | EP | disclosed |
| EP-2125736-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | Leo Pharma A/S (DK) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008077404-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA A/S (DK) | 2008-07-03 | — | — | WO | disclosed |
| EP-0253327-B1 | DIPHENYLPROPYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-05-06 | — | — | EP | disclosed |
| US-4988730-A | Treatment of angina or arrhythmia | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYAR RT (HU) | 1991-01-29 | — | — | US | disclosed |
| EP-0253327-A2 | Diphenylpropylamine derivatives, their preparation and their pharmaceutical use | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-01-20 | — | — | EP | disclosed |
| EP-0030749-B1 | CARBOXIMIDAMIDE DERIVATIVES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | AKZO N.V. (NL) | 1983-08-17 | — | — | EP | disclosed |
| EP-0030749-A1 | Carboximidamide derivatives, a process for preparing them and pharmaceutical preparations containing same | AKZO N.V. (NL) | 1981-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183797-A1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | HSP90AB1, HSP90AA1, HIF1AN | ACHE 4868/4885CA2 534/4885CA1 2309/4885 |
| US-20150183786-A1 | BICYCLIC AZA-AMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | BDNF, MAOA, HDAC10 | ACHE 150/4885CA2 4726/4885CA1 2505/4885 |
| US-20160340331-A1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | HSP90AB1, HSP90AA1, HSP90AB2P | ACHE 4870/4885CA2 749/4885CA1 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.