Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3416586 | 0.86 | MAP4K4 (0.45) | TSHRLTA4HPAX8SMN1; SMN2CYP1A2 | |
| SCHEMBL10341611 | 0.86 | KMT2A (0.46) | TSHRLTA4HPAX8SMN1; SMN2CYP1A2 | |
| SCHEMBL1006428 | 0.85 | PAX8 (0.63) | TSHRLTA4HPAX8SMN1; SMN2NPC1 | |
| SCHEMBL20298287 | 0.84 | MEN1 (0.46) | TSHRLTA4HPAX8SMN1; SMN2CYP1A2 | |
| SCHEMBL24262518 | 0.82 | KMT2A (0.61) | TSHRLTA4HPAX8SMN1; SMN2KMT2A | |
| SCHEMBL28985646 | 0.81 | PAX8 (0.40) | TSHRLTA4HPAX8SMN1; SMN2CYP1A2 | |
| SCHEMBL108195 | 0.81 | LTA4H (0.50) | TSHRLTA4HPAX8SMN1; SMN2CYP1A2 | |
| SCHEMBL11810231 | 0.80 | ALDH1A1 (0.41) | TSHRLTA4HPAX8SMN1; SMN2CYP1A2 | |
| SCHEMBL15952111 | 0.80 | BCL6 (0.56) | CYP1A2NPC1RAB9ACYP2C19CYP2C9 | |
| SCHEMBL28468081 | 0.78 | PIN1 (0.44) | TSHRPAX8SMN1; SMN2CYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901665-B | Use of triazolotriazine derivatives in the treatment of diseases | 浙江春禾医药科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-111051309-B | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-111164084-B | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2023-05-23 | — | — | CN | disclosed |
| US-20230048888-A1 | USE OF TRIAZOLOTRIAZINE DERIVATIVE IN TREATMENT OF DISEASES | ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) | 2023-02-16 | — | — | US | disclosed |
| EP-4083044-A1 | USE OF TRIAZOLOTRIAZINE DERIVATIVE IN TREATMENT OF DISEASES | Zhejiang Vimgreen Pharmaceuticals, Ltd (CN) | 2022-11-02 | — | — | EP | disclosed |
| CN-114901665-A | Use of triazolotriazine derivatives for the treatment of diseases | 浙江春禾医药科技有限公司 | 2022-08-12 | — | — | CN | disclosed |
| US-8865620-B2 | Heat-sensitive coating compositions based on resorcinyl triazine derivatives | DATALASE, LTD. (GB) | 2014-10-21 | — | — | US | disclosed |
| US-20110311786-A1 | HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES | DATALASE LTD | 2011-12-22 | — | — | US | disclosed |
| EP-2121853-A1 | HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES | BASF SE (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008110487-A1 | HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES | BASF SE (CH) | 2008-09-18 | — | — | WO | disclosed |
| US-3966680-A | Phenoxy-s-triazine chain coupler for polyesterification and novel polyesters | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110311786-A1 | HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES | OR10J3, NR3C2, NR1H2 | TSHR 299/4885LTA4H 2605/4885PAX8 1375/4885 |
| US-20230048888-A1 | USE OF TRIAZOLOTRIAZINE DERIVATIVE IN TREATMENT OF DISEASES | TPMT, TPP2, TMPRSS15 | TSHR 805/4885LTA4H 511/4885PAX8 4731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.