SCHEMBL2167792

SCHEMBL2167792

C=C(C)COCCC[Si](CC)(CC)Oc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.36
TSHR P16473 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GPR174 Q9BXC1 1/20 0.33
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
ALOX12 P18054 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
PAX8 Q06710 1/20 0.31
LTA4H P09960 1/20 0.31
KCNA3 P22001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2166943 0.86 RECQL (0.36) RECQLTSHRL3MBTL1SMN1; SMN2GPR174
SCHEMBL1857566 0.84 L3MBTL1 (0.36) RECQLTSHRL3MBTL1SMN1; SMN2GPR174
SCHEMBL8899639 0.84 L3MBTL1 (0.36) RECQLTSHRL3MBTL1SMN1; SMN2GPR174
SCHEMBL852399 0.83 L3MBTL1 (0.35) RECQLTSHRL3MBTL1SMN1; SMN2GPR174
SCHEMBL4444485 0.83 L3MBTL1 (0.35) RECQLTSHRL3MBTL1SMN1; SMN2GPR174
SCHEMBL9843714 0.79 PAX8 (0.36) RECQLTSHRL3MBTL1GPR174LMNA
SCHEMBL2167795 0.78 TDP1 (0.47) RECQLTSHRL3MBTL1SMN1; SMN2LMNA
SCHEMBL704094 0.78 LTA4H (0.38) RECQLTSHRL3MBTL1LTA4HKCNA3
SCHEMBL704883 0.78 LTA4H (0.38) RECQLTSHRL3MBTL1LTA4HKCNA3
SCHEMBL4807090 0.75 GPR174 (0.32) RECQLTSHRGPR174MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1950239-B1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO LTD (JP) 2017-01-04 EP disclosed
US-7985476-B2 Transparent zirconia dispersion and zirconia particle-containing resin composition, composition for sealing light emitting element and light emitting element, hard coat film and optical functional film and optical component, and method for producing zirconia particle-containing resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2011-07-26 US disclosed
US-20090140284-A1 Transparent Inorganic Oxide Dispersion and Iorganic Oxide Particle-Containing Resin Composition, Composition for Sealing Light Emitting Element and Light Emitting element, Hard Coat Film and Optical Functional Film and Optical Component, and Method for Producing Inorganic Oxide Pariticle-Containing Resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2009-06-04 US disclosed
EP-1950239-A1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2008-07-30 EP disclosed