SCHEMBL4444910

SCHEMBL4444910

COc1ccc(C=CC=O)cc1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 2/20 0.76
ALDH1A1 P00352 2/20 0.69
AOX1 Q06278 1/20 0.69
TUBB1 Q9H4B7 8/20 0.65
TUBB4A P04350 2/20 0.65
TUBB P07437 2/20 0.65
TUBA3C P0DPH7 2/20 0.65
TUBA1B P68363 2/20 0.65
TUBA4A P68366 2/20 0.65
TUBB4B P68371 2/20 0.65
TUBB3 Q13509 2/20 0.65
TUBB2A Q13885 2/20 0.65
TUBB8 Q3ZCM7 2/20 0.65
TUBA3E Q6PEY2 2/20 0.65
TUBA1A Q71U36 2/20 0.65
TUBA1C Q9BQE3 2/20 0.65
TUBB6 Q9BUF5 2/20 0.65
TUBB2B Q9BVA1 2/20 0.65
APP P05067 3/20 0.65
ALOX5 P09917 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38660877 1.00 XDH (0.76) XDHALDH1A1AOX1TUBB1TUBB4A
SCHEMBL2689738 1.00 XDH (0.76) XDHALDH1A1AOX1TUBB1TUBB4A
SCHEMBL21798687 0.87 TUBB1 (0.81) XDHALDH1A1AOX1TUBB1TUBB4A
Coniferyl Aldehyde SCHEMBL13144559 0.86 XDH (1.00) XDHALDH1A1APPALOX5ABCB1
Coniferyl Aldehyde SCHEMBL167835 0.86 XDH (1.00) XDHALDH1A1APPALOX5ABCB1
Coniferyl Aldehyde SCHEMBL30365777 0.86 XDH (1.00) XDHALDH1A1APPALOX5ABCB1
Coniferyl Aldehyde SCHEMBL29404938 0.86 XDH (1.00) XDHALDH1A1APPALOX5ABCB1
Coniferyl Aldehyde SCHEMBL198485 0.86 XDH (1.00) XDHALDH1A1APPALOX5ABCB1
3,4-Dimethoxy Cinnamaldehyde SCHEMBL563071 0.84 XDH (0.72) XDHALDH1A1TUBB1TUBB4ATUBB
3,4-Dimethoxy Cinnamaldehyde SCHEMBL3000359 0.84 XDH (0.72) XDHALDH1A1TUBB1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118439939-A Synthesis process of Edwan sweet intermediate 3-hydroxy-4-methoxy cinnamaldehyde 暨南大学 2024-08-06 CN claimed
CN-113620792-A Preparation method of 3-hydroxy-4-methoxy phenylpropylaldehyde 绵阳三香汇生物科技有限公司 2021-11-09 CN claimed
US-9512063-B2 Process for the preparation of advantame DIVI'S LABORATORIES LIMITED (IN) 2016-12-06 US claimed
EP-1283197-B1 PROCESS FOR PRODUCING CINNAMYLALDEHYDE DERIVATIVES, USE THEREOF AND THE LIKE AJINOMOTO KK (JP) 2009-10-21 EP claimed
US-7141263-B2 Process for producing cinnamaldehyde derivatives, use thereof and the like AJINOMOTO CO., INC. (JP) 2006-11-28 US claimed
US-6965055-B2 Process for producing cinnamaldehyde derivatives, use thereof and the like AJINOMOTO CO., LTD. (JP) 2005-11-15 US claimed
US-20050245759-A1 Process for producing cinnamaldehyde derivatives, use thereof and the like AJINOMOTO CO., INC. (JP) 2005-11-03 US claimed
US-20040261198-A1 Restructuring and finishing of keratin fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-12-30 US claimed
US-20040176472-A1 Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof AJINOMOTO CO., INC. (JP) 2004-09-09 US claimed
US-20030163004-A1 Process for producing cinnamaldehyde derivatives, use thereof and the like AJINOMOTO CO., INC. (JP) 2003-08-28 US claimed
EP-1283197-A1 PROCESS FOR PRODUCING CINNAMYLALDEHYDE DERIVATIVES, USE THEREOF AND THE LIKE Ajinomoto Co., Inc. (JP) 2003-02-12 EP claimed
US-20020133037-A1 Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof AJINOMOTO CO. INC (JP) 2002-09-19 US claimed
EP-1231215-A1 PROCESS FOR THE PRODUCTION OF ASPARTYLDIPEPTIDE ESTER DERIVATIVES, NOVEL INTERMEDIATES THEREFOR AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES Ajinomoto Co., Inc. (JP) 2002-08-14 EP claimed
CN-121318687-A Preparation method of Edwansweet intermediate 3-hydroxy-4-methoxy phenylpropionaldehyde 宁夏万香源生物科技有限公司 2026-01-13 CN disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
EP-1231215-A1 PROCESS FOR THE PRODUCTION OF ASPARTYLDIPEPTIDE ESTER DERIVATIVES, NOVEL INTERMEDIATES THEREFOR AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES Ajinomoto Co., Inc. (JP) 2002-08-14 EP disclosed
WO-2001087813-A1 PROCESS FOR PRODUCING CINNAMYLALDEHYDE DERIVATIVES, USE THEREOF AND THE LIKE AJINOMOTO CO., INC. (JP) 2001-11-22 WO disclosed
EP-1034903-A1 METHOD FOR THE TREATMENT OF WOOD WITH METALLIC TREATMENT AND WOOD TREATED BY THE METHOD Showa Denko Kabushiki Kaisha (JP) 2000-09-13 EP disclosed
EP-0953634-A1 COMPOSITION FOR TREATING POROUS ARTICLE, TREATMENT METHOD, AND USE THEREOF SHOWA DENKO KABUSHIKI KAISHA (JP) 1999-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020133037-A1 Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof DPP4, DNPEP, IAPP XDH 2203/4885ALDH1A1 517/4885AOX1 2545/4885
US-20050245759-A1 Process for producing cinnamaldehyde derivatives, use thereof and the like ALDH7A1, GOT1, FARS2 XDH 1573/4885ALDH1A1 45/4885AOX1 462/4885
US-20030163004-A1 Process for producing cinnamaldehyde derivatives, use thereof and the like ALDH7A1, ASPH, AASDHPPT XDH 1430/4885ALDH1A1 51/4885AOX1 575/4885
US-20040176472-A1 Process for production of aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for production thereof DPP4, DNPEP, IAPP XDH 2203/4885ALDH1A1 517/4885AOX1 2545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.