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SCHEMBL4445443

SCHEMBL4445443

CC(C)Cc1cc(CC(C)C)cc(-c2ccc3ccccc3n2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 10/20 0.47
▸ RAB9A P51151 10/20 0.47
▸ CYP1A2 P05177 3/20 0.47
▸ AR P10275 2/20 0.47
▸ CYP3A4 P08684 2/20 0.47
▸ CYP2D6 P10635 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ KDM4E B2RXH2 7/20 0.47
▸ SMN1; SMN2 Q16637 6/20 0.47
▸ ALDH1A1 P00352 6/20 0.47
▸ NFKB1 P19838 2/20 0.46
▸ NFKB2 Q00653 2/20 0.46
▸ RELA Q04206 2/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ MAPT P10636 5/20 0.45
▸ HSD17B10 Q99714 3/20 0.45
▸ TP53 P04637 2/20 0.45
▸ PKM P14618 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4445412 0.88 NPC1 (0.48) NPC1RAB9ACYP1A2ARCYP3A4
SCHEMBL20809321 0.78 DHODH (0.51) NPC1RAB9ACYP1A2ARCYP3A4
SCHEMBL26836493 0.78 HTR2A (0.46) NPC1RAB9ACYP1A2ARCYP3A4
SCHEMBL20809122 0.77 DHODH (0.50) NPC1RAB9ACYP1A2ARCYP3A4
SCHEMBL26836406 0.77 HTR2A (0.49) NPC1RAB9ACYP1A2ARCYP3A4
SCHEMBL20198461 0.76 NPC1 (0.45) NPC1RAB9ACYP1A2ARCYP3A4
SCHEMBL16291956 0.75 CYP1A2 (0.40) CYP1A2KDM4ESMN1; SMN2ALDH1A1MEN1
SCHEMBL7005582 0.75 NPC1 (0.44) NPC1RAB9ACYP1A2ARCYP3A4
SCHEMBL4436058 0.74 DHODH (0.39) NPC1RAB9ACYP1A2KDM4EMEN1
SCHEMBL29987195 0.73 NPC1 (0.47) NPC1RAB9ACYP1A2ARCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11495755-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-08 — — US disclosed
EP-3719099-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2022-09-14 — — EP disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 — — EP disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 — — EP disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
EP-3327100-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2020-05-06 — — EP disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 — — US disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 — — US disclosed
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-23 — — US disclosed
US-20100090591-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-04-15 — — US disclosed
US-20100090591-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-04-15 — — US disclosed
WO-2010033550-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-25 — — WO disclosed
CN-101657518-A phosphorescent material UNIV DISPLAY CORP US 2010-02-24 — — CN disclosed
EP-2121871-A2 PHOSPHORESCENT MATERIALS University Display Corporation (US) 2009-11-25 — — EP disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 — — WO disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility PCID2, ICMT, ORAI2 NPC1 3616/4885RAB9A 1685/4885CYP1A2 1511/4885
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RUVBL2, TERT, OR10J3 NPC1 4327/4885RAB9A 1698/4885CYP1A2 2665/4885
US-11495755-B2 Organic electroluminescent materials and devices RUVBL2, TERT, OR10J3 NPC1 4327/4885RAB9A 1698/4885CYP1A2 2665/4885
US-10600975-B2 Organic electroluminescent materials and devices TERT, OR10J3, RUVBL2 NPC1 4327/4885RAB9A 1716/4885CYP1A2 1792/4885
US-20100090591-A1 PHOSPHORESCENT MATERIALS PPA1, PHOSPHO1, PPP1CC NPC1 2727/4885RAB9A 1459/4885CYP1A2 4756/4885
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, PORCN NPC1 3813/4885RAB9A 2720/4885CYP1A2 4411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.