SCHEMBL4436058

SCHEMBL4436058

Cc1cc(C)cc(-c2ccc3ccc(CC(C)C)cc3n2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.39
KDM4E B2RXH2 1/20 0.36
XDH P47989 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
CYP1A2 P05177 1/20 0.33
CLK1 P49759 1/20 0.32
CLK2 P49760 1/20 0.32
HIPK1 Q86Z02 1/20 0.32
HIPK2 Q9H2X6 1/20 0.32
HIPK3 Q9H422 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
TACR1 P25103 2/20 0.32
ABL1 P00519 1/20 0.32
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
MEN1 O00255 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17453335 0.90 DHODH (0.41) DHODHKDM4EXDHCLK1CLK2
SCHEMBL19389194 0.90 DHODH (0.38) DHODHKDM4EXDHGABRA1GABRB2
SCHEMBL20809319 0.87 CTSS (0.40) DHODHKDM4EXDHCTSSCTSK
SCHEMBL18508278 0.86 CTSS (0.36) DHODHKDM4ENOS2CTSSCTSK
SCHEMBL28355002 0.83 ALOX5AP (0.38) DHODHKDM4EXDH
SCHEMBL20809321 0.83 DHODH (0.51) DHODHKDM4EXDHCYP1A2CTSS
SCHEMBL14953505 0.83 KMT2A (0.36) DHODHKDM4ENOS3NOS1NOS2
SCHEMBL14953322 0.81 GABRA1 (0.36) DHODHKDM4EXDHGABRA1GABRB2
SCHEMBL21577555 0.80 AR (0.37) DHODHKDM4EXDHGABRA1GABRB2
SCHEMBL30012119 0.80 DHODH (0.36) DHODHKDM4EXDHGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917907-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-02-27 US disclosed
WO-2023082897-A1 METAL IRIDIUM COMPLEX AND APPLICATION THEREOF 广东阿格蕾雅光电材料有限公司 2023-05-19 WO disclosed
US-11584719-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-02-21 US disclosed
WO-2022267941-A1 ORGANOMETALLIC IRIDIUM COMPOUND 广东阿格蕾雅光电材料有限公司 2022-12-29 WO disclosed
WO-2022262662-A1 ORGANOMETALLIC COMPOUND, AND APPLICATION THEREOF 四川阿格瑞新材料有限公司 2022-12-22 WO disclosed
US-20220402877-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-22 US disclosed
WO-2022262309-A1 ORGANOMETALLIC IRIDIUM COMPOUND AND APPLICATION THEREOF 广东阿格蕾雅光电材料有限公司 2022-12-22 WO disclosed
US-11527728-B2 Organic electroluminescent compounds and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2022-12-13 US disclosed
US-11495755-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-08 US disclosed
EP-3719099-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2022-09-14 EP disclosed
EP-2465912-A1 Phosphorescent Materials Universal Display Corporation (US) 2012-06-20 EP disclosed
US-20100090591-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-04-15 US disclosed
US-20100090591-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-04-15 US disclosed
WO-2010033550-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-25 WO disclosed
EP-2121871-A2 PHOSPHORESCENT MATERIALS University Display Corporation (US) 2009-11-25 EP disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 US disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 WO disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility PCID2, ICMT, ORAI2 DHODH 1363/4885KDM4E 2381/4885XDH 2040/4885
US-11527728-B2 Organic electroluminescent compounds and organic electroluminescent device comprising the same VDAC1, VDAC2, VAPA DHODH 2981/4885KDM4E 2458/4885XDH 1727/4885
US-20220402877-A1 ELECTROLUMINESCENT DEVICE MCOLN2, MCOLN1, LDHB DHODH 1700/4885KDM4E 1211/4885XDH 279/4885
US-11584719-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, SOD1, TELO2 DHODH 1845/4885KDM4E 1410/4885XDH 1795/4885
US-11495755-B2 Organic electroluminescent materials and devices RUVBL2, TERT, OR10J3 DHODH 3626/4885KDM4E 3403/4885XDH 1368/4885
US-20100090591-A1 PHOSPHORESCENT MATERIALS PPA1, PHOSPHO1, PPP1CC DHODH 3574/4885KDM4E 3913/4885XDH 4666/4885
US-11917907-B2 Organic electroluminescent device SOD1, TRPC6, L1CAM DHODH 2705/4885KDM4E 2489/4885XDH 3101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.