Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439090 | 0.84 | SCN9A (0.42) | LTA4HALDH1A1LMNAMAPTGRM2 | |
| SCHEMBL4439837 | 0.84 | SCN9A (0.42) | LTA4HALDH1A1LMNAMAPTGRM2 | |
| SCHEMBL4437663 | 0.84 | SCN9A (0.42) | LTA4HALDH1A1LMNAMAPTGRM2 | |
| SCHEMBL4434058 | 0.82 | KCNH2 (0.45) | GRM2NPC1RAB9AKMT2A | |
| SCHEMBL8789320 | 0.79 | GRM2 (0.43) | ALDH1A1LMNAMAPTGRM2KMT2A | |
| SCHEMBL4444305 | 0.77 | KCNH2 (0.47) | GRM2NPC1RAB9AKMT2A | |
| SCHEMBL4439973 | 0.75 | PBRM1 (0.44) | ALDH1A1LMNAMAPTGRM2KMT2A | |
| SCHEMBL3591132 | 0.75 | PRKCZ (0.44) | PRKCZLTA4HALDH1A1LMNATP53 | |
| SCHEMBL3591136 | 0.75 | PRKCZ (0.44) | PRKCZLTA4HALDH1A1LMNATP53 | |
| SCHEMBL4439829 | 0.73 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |