Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466772 | 0.91 | ALDH1A1 (0.51) | KDM4EALDH1A1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL1725253 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL50243 | 0.80 | MEN1 (0.55) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL12182365 | 0.79 | BRD4 (0.50) | ALDH1A1HTTSMN1; SMN2HPGDTSHR | |
| SCHEMBL8495853 | 0.76 | CETP (0.47) | KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL27339399 | 0.75 | SMN1; SMN2 (0.85) | KDM4EALDH1A1SMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL31281717 | 0.75 | ATR (0.44) | KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL22264710 | 0.75 | WNT3 (0.66) | KDM4EALDH1A1HTTSMN1; SMN2HPGD | |
| SCHEMBL31321007 | 0.75 | WNT3 (0.66) | KDM4EALDH1A1HTTSMN1; SMN2HPGD | |
| SCHEMBL16843387 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1HTTHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233940-A1 | Insecticide Compositions | TAYLOR GEORGE | 2009-09-17 | — | — | US | disclosed |
| US-20090156399-A1 | Synergistic Insecticide Mixtures | BAYER CROPSCIENCE AG (DE) | 2009-06-18 | — | — | US | disclosed |
| US-20080274882-A1 | Insecticides Based on Selected Neonicotinoids and Strobilurins | BAYER CROPSCIENCE AG (DE) | 2008-11-06 | — | — | US | disclosed |
| US-20080261811-A1 | Synergistic Mixtures Exhibiting Insecticidal and Fungicidal Action | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | US | disclosed |
| US-20080139388-A1 | Synergistic Insecticide Mixtures | BAYER CROPSCIENCE AG (DE) | 2008-06-12 | — | — | US | disclosed |
| US-6849744-B2 | α-phenyl-β-keto sulfones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| US-6806292-B2 | SUCH AS N-CYANO-N'-CYCLOHEXYL-ETH-1-YL-ETHANE-AMIDINE; PESTICIDES, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-10-19 | — | — | US | disclosed |
| US-20040122227-A1 | Cyclic guanidine derivatives and their use as pesticides | WAGNER KLAUS (DE) | 2004-06-24 | — | — | US | disclosed |
| US-6734198-B1 | SUCH AS 5-CHLORO-2-(3,4,4- TRIFLUORO-3-BUTENYLTHIO)THIAZOLE | NIHON BAYER AGROCHEM K.K. (JP) | 2004-05-11 | — | — | US | disclosed |
| US-20040063669-A1 | Alpha-phenyl-beta-ketosulfone | FISCHER REINER (DE) | 2004-04-01 | — | — | US | disclosed |
| US-6683028-B1 | Cyclic guanidine derivatives and their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-27 | — | — | US | disclosed |
| US-6670385-B1 | Fungicides, herbicides and insecticides for crops | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | disclosed |
| US-20030109702-A1 | Fungicides, bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-12 | — | — | US | disclosed |
| US-20030100613-A1 | Substituted imide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-29 | — | — | US | disclosed |
| US-6562856-B1 | The invention relates to novel pyrazolyl benzyl ethers, to a process for their preparation and to their use for controlling harmful organisms, bactericides and fungicide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-13 | — | — | US | disclosed |
| US-6518296-B1 | For controlling at least one pest selected from the group consisting of insects, arachnids and nematodes | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-11 | — | — | US | disclosed |
| US-6369093-B1 | Pyrazole carboxanilide fungicide | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100613-A1 | Substituted imide derivatives | DDT, CBR3, CBR1 | KDM4E 1271/4885ALDH1A1 998/4885HTT 3888/4885 |
| US-20080274882-A1 | Insecticides Based on Selected Neonicotinoids and Strobilurins | STMN2, STMN1, DDX6 | KDM4E 4667/4885ALDH1A1 1443/4885HTT 3159/4885 |
| US-20030109702-A1 | Fungicides, bactericides | BTD, CYP51A1, DDT | KDM4E 436/4885ALDH1A1 2530/4885HTT 1636/4885 |
| US-20040122227-A1 | Cyclic guanidine derivatives and their use as pesticides | PRMT1, GUCY1A1, GUCY1A2 | KDM4E 1669/4885ALDH1A1 881/4885HTT 3259/4885 |
| US-20040063669-A1 | Alpha-phenyl-beta-ketosulfone | CYP2S1, SULT1E1, SKP1 | KDM4E 669/4885ALDH1A1 704/4885HTT 2556/4885 |
| US-20080139388-A1 | Synergistic Insecticide Mixtures | MAT2B, DDT, MSRB3 | KDM4E 1504/4885ALDH1A1 3522/4885HTT 921/4885 |
| US-20090156399-A1 | Synergistic Insecticide Mixtures | NISCH, SCN3A, CYP51A1 | KDM4E 3525/4885ALDH1A1 3702/4885HTT 3699/4885 |
| US-20080261811-A1 | Synergistic Mixtures Exhibiting Insecticidal and Fungicidal Action | MLX, BROX, BMX | KDM4E 1634/4885ALDH1A1 3734/4885HTT 3868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.