Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645320 | 0.64 | CFTR (0.32) | ALDH1A1KDM4EGAAMAPTTDP1 | |
| SCHEMBL10630454 | 0.64 | TDP1 (0.52) | ALDH1A1KDM4EGAAMAPTTDP1 | |
| SCHEMBL5012600 | 0.63 | GAA (0.52) | ALDH1A1KDM4EGAAMAPTTDP1 | |
| SCHEMBL8979742 | 0.59 | GAA (0.37) | KDM4EGAAHPGDGSK3AGSK3B | |
| SCHEMBL30116334 | 0.59 | MGLL (0.44) | ALDH1A1GAAMAPTTDP1GRK5 | |
| SCHEMBL10773382 | 0.59 | — | — | |
| SCHEMBL3257577 | 0.58 | SIGMAR1 (0.58) | KDM4EGAAMAPTTDP1MEN1 | |
| SCHEMBL9717767 | 0.58 | ALDH1A1 (0.37) | ALDH1A1KDM4EGAAMAPTTDP1 | |
| SCHEMBL9521015 | 0.58 | CYP3A4 (0.43) | KDM4EGAAMAPTTDP1GRK5 | |
| SCHEMBL21694447 | 0.58 | MAPT (0.38) | ALDH1A1KDM4EGAAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080026486-A1 | Assay Methods, Materials and Preparations | AKUBIO LIMITED (GB) | 2008-01-31 | — | — | US | claimed |
| EP-1799720-A1 | ASSAY METHODS, MATERIALS AND PREPARATIONS | Akubio Limited (GB) | 2007-06-27 | — | — | EP | claimed |
| WO-2006027582-A1 | ASSAY METHODS, MATERIALS AND PREPARATIONS | AKUBIO LIMITED (GB) | 2006-03-16 | — | — | WO | claimed |
| US-20090275721-A1 | Coating Surfaces | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-11-05 | — | — | US | disclosed |
| EP-1996944-A1 | IMPROVEMENTS IN OR RELATING TO COATING SURFACES | Inverness Switzerland GmbH (CH) | 2008-12-03 | — | — | EP | disclosed |
| US-20080026486-A1 | Assay Methods, Materials and Preparations | AKUBIO LIMITED (GB) | 2008-01-31 | — | — | US | disclosed |
| WO-2007104994-A1 | IMPROVEMENTS IN OR RELATING TO COATING SURFACES | INVERNESS SWITZERLAND GMBH (CH) | 2007-09-20 | — | — | WO | disclosed |
| EP-1799720-A1 | ASSAY METHODS, MATERIALS AND PREPARATIONS | Akubio Limited (GB) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006027582-A1 | ASSAY METHODS, MATERIALS AND PREPARATIONS | AKUBIO LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080026486-A1 | Assay Methods, Materials and Preparations | SCLY, ZYX, TST | ALDH1A1 2598/4885KDM4E 2313/4885GAA 2835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.