SCHEMBL445414

SCHEMBL445414

COC(=O)c1ccc(N=C=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.58
MAPT P10636 6/20 0.58
CASP3 P42574 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
CA1 P00915 4/20 0.53
CA2 P00918 4/20 0.53
TDP1 Q9NUW8 1/20 0.53
CA12 O43570 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
ALDH1A1 P00352 3/20 0.53
NPC1 O15118 5/20 0.53
SMN1; SMN2 Q16637 5/20 0.53
TSHR P16473 1/20 0.50
ACR P10323 2/20 0.49
HPGD P15428 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19351446 0.89 TSHR (0.62) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL11646899 0.86 RAB9A (0.59) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL4886214 0.84 RAB9A (0.63) RAB9AMAPTL3MBTL1TDP1ALDH1A1
SCHEMBL1421354 0.83 RAB9A (0.56) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL2350932 0.82 ALDH1A1 (0.44) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL4023712 0.81 KDM4E (0.51) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL2145992 0.80 CA1 (0.46) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL9194945 0.80 CYP3A4 (0.40) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL76337 0.80 MAPT (0.58) RAB9AMAPTCA1CA2TDP1
SCHEMBL5797419 0.80 CA12 (0.58) RAB9AMAPTCASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 380 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240154124-A1 NEGATIVE ELECTRODE PLATE AND LITHIUM-ION BATTERY COMPRISING SAME ZHUHAI COSMX BATTERY CO., LTD. (CN) 2024-05-09 US claimed
CN-117402418-A High-wear-resistance rubber hose and preparation method thereof 河北润驰流体科技有限公司 2024-01-16 CN claimed
CN-114195671-A Asymmetric malonanilide compound and synthesis method thereof 河南师范大学 2022-03-18 CN claimed
US-10352917-B2 Carboxylate-bridged binuclear iron-sulfur clusters fluorescent probe, preparation method and application thereof DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2019-07-16 US claimed
US-20170131256-A1 CARBOXYLATE-BRIDGED BINUCLEAR IRON-SULFUR CLUSTERS FLOURESCENT PROBE, PREPARATION METHOD AND APPLICATION THEREOF DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2017-05-11 US claimed
EP-2445345-B1 BENZAMIDE DERIVATIVES TRANSLATIONAL GENOMICS RES INST (US) 2014-08-27 EP claimed
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
EP-4642766-A1 COMPOUNDS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-11-05 EP disclosed
US-20250281424-A1 SMALL MOLECULE ANTAGONISTS OF PF4 ZHOU YUHANG (US) 2025-09-11 US disclosed
EP-3774961-B1 ADDUCTS OF AMINE CATALYSTS FOR PRODUCING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2025-01-15 EP disclosed
US-12161624-B2 Selective octahydro-cyclopenta[c]pyrrole negative modulators of NR2B NOVARTIS AG (CH) 2024-12-10 US disclosed
WO-2024236000-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-11-21 WO disclosed
EP-4464727-A1 ESTERIFIED ETHANOLAMINES FOR THE PREPARATION OF ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2024-11-20 EP disclosed
US-4863947-A PESTICIDES, INSECTICIDES ROHM AND HAAS (US) 1989-09-05 US disclosed
US-4663341-A Insecticidal n-aryl-3-aryl-4,5-dihydro-1h-pyrazole-1-carboxamides ROHM AND HAAS COMPANY (US) 1987-05-05 US disclosed
CN-85101497-A Process for the preparation of N-aryl-3-aryl-4, 5-dihydro-1H-pyrazole-1-carboxamides 1986-07-16 CN disclosed
EP-0153127-A2 N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects ROHM AND HAAS COMPANY (US) 1985-08-28 EP disclosed
US-4263294-A ANTITUMOUR AGENTS, ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-04-21 US disclosed
EP-0011302-A1 Maytansinoids, their production and use Takeda Chemical Industries, Ltd. (JP) 1980-05-28 EP disclosed
US-4096334-A Process for the manufacture of carbodiimides HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10352917-B2 Carboxylate-bridged binuclear iron-sulfur clusters fluorescent probe, preparation method and application thereof FECH, ME3, SDHB RAB9A 3234/4885MAPT 4059/4885CASP3 2451/4885
US-20250281424-A1 SMALL MOLECULE ANTAGONISTS OF PF4 PF4, F12, F2 RAB9A 2246/4885MAPT 1633/4885CASP3 3484/4885
US-12161624-B2 Selective octahydro-cyclopenta[c]pyrrole negative modulators of NR2B GRIN2A, GRIN2C, GRIN3A RAB9A 3086/4885MAPT 1173/4885CASP3 4252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.