SCHEMBL4455035

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1515914	0.87	CES2 (0.53)	ALDH1A1MAPTHPGDPLAUMLYCD
	SCHEMBL7600465	0.82	SLC9A1 (0.51)	ALDH1A1MAPTHPGDNCEH1MLYCD
	SCHEMBL3267963	0.78	ERN1 (0.46)	ALDH1A1MAPTHPGDMLYCD
	SCHEMBL16335573	0.78	NPC1 (0.43)	ALDH1A1HPGDPLAUCYP1A2CYP2D6
	SCHEMBL27607386	0.78	ALDH1A1 (0.67)	ALDH1A1MAPTHPGDNCEH1PLAU
	SCHEMBL4833064	0.78	KDM4E (0.64)	ALDH1A1HPGDPLAUMLYCDCYP1A2
	SCHEMBL3299767	0.78	ALDH1A1 (0.52)	ALDH1A1MAPTHPGDNCEH1CYP1A2
	SCHEMBL19763355	0.76	MLYCD (0.45)	ALDH1A1HPGDNCEH1PLAUMLYCD
	SCHEMBL49935	0.75	ALDH1A1 (1.00)	ALDH1A1MAPTHPGDHIF1ACYP1B1
	SCHEMBL13694026	0.75	MLYCD (0.44)	MAPTHPGDPLAUMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.