Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CPA3 | P15088 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575988 | 0.79 | NAALAD2 (0.47) | FOLH1GAAKDM4E | |
| SCHEMBL7575979 | 0.79 | NAALAD2 (0.47) | FOLH1GAAKDM4E | |
| SCHEMBL2360301 | 0.77 | SHMT2 (0.37) | LMNAHTTALDH1A1SHMT2GAA | |
| SCHEMBL2234954 | 0.73 | ENPEP (0.40) | FOLH1LMNAHTTALDH1A1SHMT2 | |
| SCHEMBL5509356 | 0.70 | CPA3 (0.46) | FOLH1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL4455175 | 0.69 | PPARG (0.37) | FOLH1LMNAHTTALDH1A1GAA | |
| SCHEMBL4456734 | 0.69 | PPARG (0.37) | FOLH1LMNAHTTALDH1A1GAA | |
| SCHEMBL17234481 | 0.68 | ALDH1A1 (0.60) | LMNAHTTALDH1A1GAAMEN1 | |
| SCHEMBL6558177 | 0.68 | PKLR (0.40) | LMNAHTTGAAMEN1NPC1 | |
| SCHEMBL13760292 | 0.68 | KDM4E (0.41) | FOLH1LMNAHTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |