Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755827 | 0.82 | HTT (0.59) | HTTALDH1A1CYP3A4CYP2C19ALOX5 | |
| SCHEMBL2404187 | 0.81 | LMNA (0.52) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL4452220 | 0.79 | RAB9A (0.49) | HTTALDH1A1CYP2C19SIGMAR1CTBP2 | |
| SCHEMBL1708481 | 0.79 | HTT (0.56) | HTTALDH1A1CYP3A4CYP2C19ALOX5 | |
| SCHEMBL4462525 | 0.79 | TDP1 (0.56) | HTTALDH1A1SMN1; SMN2GAACTBP2 | |
| SCHEMBL1067193 | 0.78 | HTT (0.63) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL31116682 | 0.78 | HTT (0.63) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL27640229 | 0.77 | HTT (0.53) | HTTALDH1A1CYP3A4CYP2C19ALOX5 | |
| SCHEMBL4002523 | 0.76 | ALDH1A1 (0.56) | HTTALDH1A1CYP3A4CYP2C19ALOX5 | |
| SCHEMBL2405257 | 0.74 | CCR5 (0.62) | HTTALDH1A1ALOX5SIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | CONSEJO SUPERIOR DE (ES) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | BAX, BCL2, CASP3 | HTT 3489/4885ALDH1A1 1468/4885CYP3A4 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.