SCHEMBL446047

SCHEMBL446047

CCc1cccc(-c2ccccc2OP(=O)(O)O)c1CC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 5/20 0.46
INPP5A Q14642 3/20 0.46
INPP5B P32019 2/20 0.46
SRC P12931 4/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
PDE3A Q14432 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HTR2A P28223 3/20 0.38
HTR2C P28335 3/20 0.38
HTR2B P41595 3/20 0.38
HTR1A P08908 1/20 0.38
PTPN5 P54829 1/20 0.37
AKT1 P31749 1/20 0.37
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3176340 0.90 INPPL1 (0.41) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL446045 0.88 L3MBTL1 (0.37) KDM4EHPGDHSD17B10PTPN5GABRA1
SCHEMBL761162 0.85 INPPL1 (0.53) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL444783 0.84 INPPL1 (0.42) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL448372 0.82 HTR2A (0.42) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL1101447 0.80 INPPL1 (0.53) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL29647909 0.80 INPPL1 (0.53) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL3259362 0.80 INPPL1 (0.43) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL9645945 0.80 INPPL1 (0.61) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL1192358 0.79 INPPL1 (0.46) INPPL1INPP5AINPP5BSRCKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421794-B1 REFRIGERATION APPARATUS DAIKIN IND LTD (JP) 2020-08-05 EP claimed
US-7527902-B2 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION (US) 2009-05-05 US claimed
US-20070026328-A1 Photoreceptor layer having phosphorus-containing lubricant XEROX CORPORATION 2007-02-01 US claimed
US-20070026330-A1 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION 2007-02-01 US claimed
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels ExxonMobil Technology and Engineering Company (US) 2026-04-28 US disclosed
US-12577493-B2 Bio-based lubricant compositions ExxonMobil Technology and Engineering Company (US) 2026-03-17 US disclosed
EP-4705417-A1 INTERNAL COMBUSTION ENGINE LUBRICANT ExxonMobil Technology and Engineering Company (US) 2026-03-11 EP disclosed
US-12534656-B2 Refrigerator oil composition and mixed composition for refrigerator IDEMITSU KOSAN CO., LTD. (JP) 2026-01-27 US disclosed
EP-4108744-B1 REFRIGERATOR OIL COMPOSITION AND MIXED COMPOSITION FOR REFRIGERATOR IDEMITSU KOSAN CO (JP) 2025-11-19 EP disclosed
EP-4101919-B1 REFRIGERATOR OIL COMPOSITION AND REFRIGERATOR MIXTURE COMPOSITION IDEMITSU KOSAN CO (JP) 2025-09-17 EP disclosed
US-12384980-B2 Internal combustion engine lubricant ExxonMobil Technology and Engineering Company (US) 2025-08-12 US disclosed
US-20250215838-A1 ENGINE LUBRICANT OPTIMIZATION FOR ADVANCED SUSTAINABLE FUELS ExxonMobil Technology and Engineering Company (US) 2025-07-03 US disclosed
US-5656577-A CONSISTS OF POLYSILOXANE BASED OILS; THIADIAZOLE DERIVATIVES, AMINE ANTIOXIDANTS AND POSPHORIC OR THIOPHOSPHORIC AND OTHER PHOSPHORUS COMPOUNDS OR CARBAMATES AS WEAR PREVENTIVE; EXCELLENT VISCOSITY AND TORQUE STABILITY TONEN CORPORATION (JP) 1997-08-12 US disclosed
EP-0778334-A1 HEAT-RESISTANT LUBRICATING OIL COMPOSITION Tonen Corporation (JP) 1997-06-11 EP disclosed
EP-0748863-A2 Traction drive fluid composition COSMO RESEARCH INSTITUTE (JP) 1996-12-18 EP disclosed
EP-0719853-A2 Fluid composition for use in fluid coupling Tonen Corporation (JP) 1996-07-03 EP disclosed
EP-0397507-B1 Silicone fluids for viscous couplings TONEN CORP (JP) 1995-03-15 EP disclosed
EP-0636682-A1 Fluid composition for fluid coupling Tonen Corporation (JP) 1995-02-01 EP disclosed
US-5332515-A Polysiloxane, phosphorus type anti-wear agent TONEN CORPORATION (JP) 1994-07-26 US disclosed
EP-0397507-A1 Silicone fluids for viscous couplings Tonen Corporation (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577493-B2 Bio-based lubricant compositions DEGS1, DSG1, DEK INPPL1 594/4885INPP5A 1449/4885INPP5B 1127/4885
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels TST, TCF4, MLLT1 INPPL1 3106/4885INPP5A 4339/4885INPP5B 3097/4885
US-12534656-B2 Refrigerator oil composition and mixed composition for refrigerator F9, CA2, F8 INPPL1 686/4885INPP5A 2394/4885INPP5B 1802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.