SCHEMBL446045

SCHEMBL446045

CCc1cccc(-c2ccccc2OP(=O)(Oc2ccccc2-c2cccc(CC)c2CC)Oc2ccccc2-c2cccc(CC)c2CC)c1CC

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.37
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
HTT P42858 2/20 0.34
GABRA1 P14867 2/20 0.33
GABRB2 P47870 2/20 0.33
GPR84 Q9NQS5 1/20 0.33
PTPN5 P54829 1/20 0.33
HPGD P15428 1/20 0.33
ATM Q13315 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
RECQL P46063 1/20 0.32
XBP1 P17861 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3176329 0.89 CTSS (0.35) L3MBTL1MAPTNPSR1HTTGPR84
SCHEMBL446047 0.88 INPPL1 (0.46) L3MBTL1MAPTNPSR1GABRA1GABRB2
SCHEMBL28642969 0.86 L3MBTL1 (0.41) L3MBTL1MAPTNPSR1HTTHPGD
SCHEMBL761161 0.84 GABRA1 (0.39) L3MBTL1MAPTNPSR1HTTGABRA1
SCHEMBL444781 0.83 CTSL (0.39) L3MBTL1HTTGPR84
SCHEMBL448370 0.81 ALOX5 (0.38) TSHR
SCHEMBL704143 0.80 L3MBTL1 (0.39) L3MBTL1MAPTNPSR1GABRA1GABRB2
SCHEMBL4451151 0.79 L3MBTL1 (0.42) L3MBTL1MAPTNPSR1HTTRECQL
SCHEMBL3836816 0.79 L3MBTL1 (0.42) L3MBTL1MAPTNPSR1HTTRECQL
SCHEMBL3259356 0.79 CTSL (0.42) L3MBTL1MAPTNPSR1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7527902-B2 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION (US) 2009-05-05 US claimed
US-20070026328-A1 Photoreceptor layer having phosphorus-containing lubricant XEROX CORPORATION 2007-02-01 US claimed
US-20070026330-A1 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION 2007-02-01 US claimed
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels ExxonMobil Technology and Engineering Company (US) 2026-04-28 US disclosed
US-12577493-B2 Bio-based lubricant compositions ExxonMobil Technology and Engineering Company (US) 2026-03-17 US disclosed
EP-4705417-A1 INTERNAL COMBUSTION ENGINE LUBRICANT ExxonMobil Technology and Engineering Company (US) 2026-03-11 EP disclosed
US-12534656-B2 Refrigerator oil composition and mixed composition for refrigerator IDEMITSU KOSAN CO., LTD. (JP) 2026-01-27 US disclosed
EP-4108744-B1 REFRIGERATOR OIL COMPOSITION AND MIXED COMPOSITION FOR REFRIGERATOR IDEMITSU KOSAN CO (JP) 2025-11-19 EP disclosed
EP-4101919-B1 REFRIGERATOR OIL COMPOSITION AND REFRIGERATOR MIXTURE COMPOSITION IDEMITSU KOSAN CO (JP) 2025-09-17 EP disclosed
US-12384980-B2 Internal combustion engine lubricant ExxonMobil Technology and Engineering Company (US) 2025-08-12 US disclosed
US-20250215838-A1 ENGINE LUBRICANT OPTIMIZATION FOR ADVANCED SUSTAINABLE FUELS ExxonMobil Technology and Engineering Company (US) 2025-07-03 US disclosed
EP-0889112-A1 LUBRICATING OIL COMPOSITION FOR AUTOMATIC TRANSMISSIONS TONEN CORPORATION (JP) 1999-01-07 EP disclosed
EP-0812900-A2 Lubricating oil composition for automatic transmission IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-12-17 EP disclosed
US-5656577-A CONSISTS OF POLYSILOXANE BASED OILS; THIADIAZOLE DERIVATIVES, AMINE ANTIOXIDANTS AND POSPHORIC OR THIOPHOSPHORIC AND OTHER PHOSPHORUS COMPOUNDS OR CARBAMATES AS WEAR PREVENTIVE; EXCELLENT VISCOSITY AND TORQUE STABILITY TONEN CORPORATION (JP) 1997-08-12 US disclosed
EP-0778334-A1 HEAT-RESISTANT LUBRICATING OIL COMPOSITION Tonen Corporation (JP) 1997-06-11 EP disclosed
EP-0748863-A2 Traction drive fluid composition COSMO RESEARCH INSTITUTE (JP) 1996-12-18 EP disclosed
EP-0397507-B1 Silicone fluids for viscous couplings TONEN CORP (JP) 1995-03-15 EP disclosed
EP-0636682-A1 Fluid composition for fluid coupling Tonen Corporation (JP) 1995-02-01 EP disclosed
US-5332515-A Polysiloxane, phosphorus type anti-wear agent TONEN CORPORATION (JP) 1994-07-26 US disclosed
EP-0397507-A1 Silicone fluids for viscous couplings Tonen Corporation (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577493-B2 Bio-based lubricant compositions DEGS1, DSG1, DEK L3MBTL1 1782/4885MAPT 2771/4885NPSR1 2018/4885
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels TST, TCF4, MLLT1 L3MBTL1 138/4885MAPT 1116/4885NPSR1 3674/4885
US-12534656-B2 Refrigerator oil composition and mixed composition for refrigerator F9, CA2, F8 L3MBTL1 3192/4885MAPT 3137/4885NPSR1 3968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.