SCHEMBL4465343

SCHEMBL4465343

CO[Si](CCCc1ccccc1O)(OC)OC

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MPO P05164 6/20 0.48
SLC6A4 P31645 2/20 0.46
TAAR1 Q96RJ0 1/20 0.46
MGLL Q99685 1/20 0.42
HTR1A P08908 1/20 0.42
HSPA5 P11021 1/20 0.42
NPC1 O15118 1/20 0.41
PKM P14618 1/20 0.41
RAB9A P51151 1/20 0.41
IDO1 P14902 2/20 0.40
AKR1B10 O60218 1/20 0.40
AKR1B1 P15121 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
ALOX5 P09917 1/20 0.39
PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31542133 0.93 MGLL (0.47) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL16669338 0.89 TAAR1 (0.48) MPOSLC6A4TAAR1HTR1AHSPA5
SCHEMBL1639308 0.87 MTNR1A (0.40) MPOTAAR1IDO1ALOX5PTGS2
SCHEMBL12713545 0.84 MPO (0.45) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL399635 0.83 MPO (0.44) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL16668945 0.83 MPO (0.44) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL10427665 0.79 MPO (0.50) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL16669267 0.79 HTR1A (0.44) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL6684267 0.79 MPO (0.46) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL16198395 0.79 ALDH1A1 (0.39) TAAR1IDO1ALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9430071-B2 Resin composition, and transparent membrane for touch panel sensors and touch panel using same DNP FINE CHEMICALS CO., LTD. (JP) 2016-08-30 US disclosed
US-20150116234-A1 RESIN COMPOSITION, AND TRANSPARENT MEMBRANE FOR TOUCH PANEL SENSORS AND TOUCH PANEL USING SAME DNP FINE CHEMICALS CO., LTD. (JP) 2015-04-30 US disclosed
US-7517925-B2 Benzoxazines, thermosetting resins comprised thereof, and methods for use thereof HENKEL CORPORATION (US) 2009-04-14 US disclosed
US-20040123948-A1 Benzoxazines, thermosetting resins comprised thereof, and methods for use thereof LOCTITE CORPORATION 2004-07-01 US disclosed
US-6743852-B2 A THERMOSETTING RESIN COMPOSITION CONTAINING A BENZOXAZINE COMPOUND WITH A POLYMERIZABLE MOITY, AND A CURING AGENT HENKEL CORPORATION 2004-06-01 US disclosed
US-20030125551-A1 Benzoxazines, thermosetting resins comprised thereof, and methods for use thereof LOCTITE CORPORATION 2003-07-03 US disclosed
WO-2003042196-A1 BENZOXAZINESHAVING POLYMERIZABLE SIDE GROUPS, THERMOSETTING RESI NS COMPRISED THEREOF, AND METHODS FOR USE THEREOF HENKEL CORPORATION (US) 2003-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030125551-A1 Benzoxazines, thermosetting resins comprised thereof, and methods for use thereof TMPO, ALOX5, KDM5A MPO 324/4885SLC6A4 3806/4885TAAR1 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.