Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170273 | 0.84 | GSTP1 (0.43) | GSTP1HDAC4HDAC2HDAC8SLC6A2 | |
| SCHEMBL31197637 | 0.83 | PRCP (0.35) | MAOB | |
| SCHEMBL4467574 | 0.83 | PRCP (0.35) | MAOB | |
| SCHEMBL26606300 | 0.81 | PNMT (0.31) | — | |
| SCHEMBL4460798 | 0.79 | HTR7 (0.38) | SLC6A3AKR1C3AKR1C2HTR2AHTR2C | |
| SCHEMBL6032655 | 0.78 | BRD4 (0.31) | — | |
| SCHEMBL6149919 | 0.78 | BRD4 (0.31) | — | |
| SCHEMBL1808402 | 0.77 | BRD4 (0.34) | AKR1C3AKR1C2 | |
| SCHEMBL29534991 | 0.77 | BRD4 (0.34) | AKR1C3AKR1C2 | |
| SCHEMBL6147883 | 0.76 | RXRA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1548023-B1 | Transition metal compound, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2013-08-14 | — | — | EP | disclosed |
| CN-100575324-C | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH | 2009-12-30 | — | — | CN | disclosed |
| US-7569651-B2 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2009-08-04 | — | — | US | disclosed |
| US-7342078-B2 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-03-11 | — | — | US | disclosed |
| CN-1249096-C | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2006-04-05 | — | — | CN | disclosed |
| US-20060020096-A1 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | SCHOTTEK JORG | 2006-01-26 | — | — | US | disclosed |
| EP-1548037-A2 | Random propylene-ethylene copolymers | Basell Polyolefine GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| EP-1548023-A2 | Transition metal compound, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins | Basell Polyolefine GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| EP-1548022-A2 | Transition metal compound, ligand system, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins | Basell Polyolefine GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| CN-1590355-A | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2005-03-09 | — | — | CN | disclosed |
| CN-1590422-A | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2005-03-09 | — | — | CN | disclosed |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-08-07 | — | — | US | disclosed |
| CN-1433435-A | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-07-30 | — | — | CN | disclosed |
| EP-1250365-A2 | TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS | Basell Polypropylen GmbH (DE) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001048034-A2 | TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | PORCN, PGR, PPOX | GSTP1 827/4885HDAC4 2011/4885HDAC2 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.