Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024509 | 0.86 | PTAFR (0.34) | PTAFRNPC1RAB9ALMNATP53 | |
| SCHEMBL5086245 | 0.83 | PTAFR (0.34) | PTAFRNPC1RAB9ALMNATP53 | |
| SCHEMBL27199723 | 0.80 | TSHR (0.37) | PTAFRNPC1RAB9ALMNATP53 | |
| SCHEMBL5690313 | 0.80 | BRD4 (0.38) | PTAFRNPC1RAB9ALMNATP53 | |
| SCHEMBL2388282 | 0.80 | NPC1 (0.35) | PTAFRNPC1RAB9ALMNATP53 | |
| Hydrochloric Acid SCHEMBL5697214 | 0.79 | KIF11 (0.37) | PTAFRNPC1RAB9ALMNATP53 | |
| SCHEMBL1799580 | 0.72 | NPC1 (0.33) | PTAFRNPC1RAB9ALMNATP53 | |
| SCHEMBL30541994 | 0.72 | NPC1 (0.33) | PTAFRNPC1RAB9ALMNATP53 | |
| SCHEMBL1455223 | 0.71 | NPC1 (0.36) | PTAFRNPC1RAB9ALMNATP53 | |
| SCHEMBL5689983 | 0.71 | BRD4 (0.36) | PTAFRNPC1RAB9ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124618-A1 | Asymmetric Constrained Geometry Catalysts | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2024-04-18 | — | — | US | disclosed |
| US-11802170-B2 | Polyolefins prepared with binuclear metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-10-31 | — | — | US | disclosed |
| US-20220372178-A1 | Polyolefins Prepared with Binuclear Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2022-11-24 | — | — | US | disclosed |
| EP-1548023-B1 | Transition metal compound, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2013-08-14 | — | — | EP | disclosed |
| US-7569651-B2 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2009-08-04 | — | — | US | disclosed |
| US-7342078-B2 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-03-11 | — | — | US | disclosed |
| US-20060020096-A1 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | SCHOTTEK JORG | 2006-01-26 | — | — | US | disclosed |
| EP-1548037-A2 | Random propylene-ethylene copolymers | Basell Polyolefine GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| EP-1548022-A2 | Transition metal compound, ligand system, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins | Basell Polyolefine GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| EP-1548023-A2 | Transition metal compound, catalyst system and the use of the latter for the polymerisation and copolymerisation of olefins | Basell Polyolefine GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11802170-B2 | Polyolefins prepared with binuclear metallocene catalysts | C1S, C9, C5 | PTAFR 1184/4885NPC1 3585/4885RAB9A 3673/4885 |
| US-20240124618-A1 | Asymmetric Constrained Geometry Catalysts | GNE, ESR1, PGR | PTAFR 2966/4885NPC1 3941/4885RAB9A 4202/4885 |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | PORCN, PGR, PPOX | PTAFR 818/4885NPC1 4292/4885RAB9A 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.