Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 13/20 | 0.36 |
| ▸ | CTSS | P25774 | 10/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213748 | 0.85 | KDM4E (0.44) | HSD17B10KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7219744 | 0.76 | KCNH2 (0.42) | HSD17B10KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL6184247 | 0.75 | MBOAT4 (0.45) | HSD17B10KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7215435 | 0.72 | L3MBTL1 (0.39) | HSD17B10KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL1734031 | 0.69 | KDM4E (0.43) | HSD17B10KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL19303144 | 0.69 | ALDH1A1 (0.47) | HSD17B10KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL13761490 | 0.68 | L3MBTL1 (0.36) | HSD17B10KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL20201194 | 0.68 | L3MBTL1 (0.40) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL24611859 | 0.67 | KCNH2 (0.52) | ALDH1A1LMNA | |
| SCHEMBL846285 | 0.67 | KLKB1 (0.42) | KDM4EALDH1A1MAPTHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601736-B2 | Such as 3,4-dihydro-pyrano[3,4-c]pyridine-1-on; cytokine suppressive antiinflammatory drugs; analgesics | SK CHEMICALS CO., LTD. (KR) | 2009-10-13 | — | — | US | disclosed |
| US-20070254909-A1 | Novel Pyridine Derivatives, a Process for Their Preparation and a Pharmaceutical Composition Containing the Same | SK CHEMICALS CO., LTD. (KR) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254909-A1 | Novel Pyridine Derivatives, a Process for Their Preparation and a Pharmaceutical Composition Containing the Same | IL5, IL1B, P2RY4 | HSD17B10 3499/4885KDM4E 405/4885ALDH1A1 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.