Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 14/20 | 0.41 |
| ▸ | CTSS | P25774 | 11/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219744 | 0.86 | KCNH2 (0.42) | KDM4EHSD17B10MAPK1MEN1ALDH1A1 | |
| SCHEMBL4469504 | 0.85 | HSD17B10 (0.40) | KDM4EHSD17B10CTSKCTSSMAPK1 | |
| SCHEMBL20201194 | 0.81 | L3MBTL1 (0.40) | KDM4ECTSKMAPK1RECQLMEN1 | |
| SCHEMBL6184247 | 0.81 | MBOAT4 (0.45) | KDM4EHSD17B10CTSKCTSSMEN1 | |
| SCHEMBL7215435 | 0.79 | L3MBTL1 (0.39) | KDM4EHSD17B10MAPK1MEN1ALDH1A1 | |
| SCHEMBL14534324 | 0.76 | AR (0.39) | KDM4ECTSKCTSSMAPK1RECQL | |
| SCHEMBL7219988 | 0.75 | CTSK (0.42) | CTSKCTSSMAPK1RECQL | |
| SCHEMBL13761490 | 0.74 | L3MBTL1 (0.36) | KDM4EHSD17B10MAPK1MEN1ALDH1A1 | |
| SCHEMBL16548416 | 0.72 | KDM4E (0.41) | KDM4EHSD17B10CTSKCTSSMAPK1 | |
| SCHEMBL26537080 | 0.72 | PDE3B (0.36) | KDM4EHSD17B10CTSKCTSSMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |