Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213748 | 0.86 | KDM4E (0.44) | ALDH1A1KDM4EMAPK1HSD17B10MEN1 | |
| SCHEMBL19303144 | 0.79 | ALDH1A1 (0.47) | KCNH2ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL14534341 | 0.78 | AR (0.42) | ALDH1A1L3MBTL1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7219805 | 0.77 | NOS2 (0.42) | ALDH1A1L3MBTL1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7215435 | 0.76 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1KDM4EHPGDMAPK1 | |
| SCHEMBL4469504 | 0.76 | HSD17B10 (0.40) | ALDH1A1KDM4EHPGDMAPK1HSD17B10 | |
| SCHEMBL9983754 | 0.74 | CNR1 (0.37) | KCNH2ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL22166117 | 0.73 | KCNH2 (0.47) | KCNH2ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL7219978 | 0.72 | HPGD (0.56) | ALDH1A1L3MBTL1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6184247 | 0.71 | MBOAT4 (0.45) | ALDH1A1KDM4ENPSR1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |