SCHEMBL45318

SCHEMBL45318

COC(=O)c1cc(C(=O)O)nn1-c1ncccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MALT1 Q9UDY8 5/20 0.39
RBP4 P02753 1/20 0.39
RPA1 P27694 2/20 0.39
MARS1 P56192 2/20 0.39
NTRK1 P04629 2/20 0.38
PPP1CA P62136 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL384694 0.92 ALDH1A1 (0.45) KMT2AMEN1ALDH1A1MALT1RBP4
SCHEMBL384656 0.87 KMT2A (0.43) KMT2AMEN1MALT1RPA1MARS1
SCHEMBL23249321 0.85 DHODH (0.45) ALDH1A1MALT1RBP4
SCHEMBL44760 0.85 MALT1 (0.39) ALDH1A1MALT1RBP4
SCHEMBL29504162 0.85 DHODH (0.45) ALDH1A1MALT1RBP4
SCHEMBL45319 0.84 MALT1 (0.37) ALDH1A1MALT1RBP4
SCHEMBL421559 0.83 MALT1 (0.38) KMT2AMEN1ALDH1A1MALT1RBP4
SCHEMBL45109 0.83 MALT1 (0.38) ALDH1A1MALT1RBP4
SCHEMBL30206595 0.83 MALT1 (0.38) KMT2AMEN1ALDH1A1MALT1RBP4
SCHEMBL2623669 0.83 MALT1 (0.39) KMT2AMEN1ALDH1A1MALT1RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582688-B1 ANTHRANILIC ACID DIAMIDE DERIVATIVES BAYER IP GMBH (DE) 2015-10-07 EP disclosed
US-8791139-B2 Anthranilic diamide derivatives BAYER CROPSCIENCE AG (DE) 2014-07-29 US disclosed
EP-2582688-A1 ANTHRANILIC ACID DIAMIDE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2013-04-24 EP disclosed
CN-103068813-A Anthranilic acid diamide derivatives BAYER CROPSCIENCE AG 2013-04-24 CN disclosed
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2012-01-19 US disclosed
WO-2011157654-A1 ANTHRANILIC ACID DIAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2011-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES DDT, QDPR, ANTXR2 KMT2A 1173/4885MEN1 1583/4885ALDH1A1 732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.