SCHEMBL4476448

SCHEMBL4476448

N=C(c1ccc(F)cc1)c1ccc(F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
BCL2L1 Q07817 1/20 0.44
BAD Q92934 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
HBB P68871 1/20 0.44
PTPN1 P18031 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
LTA4H P09960 1/20 0.41
IDO1 P14902 2/20 0.39
ORAI1 Q96D31 1/20 0.39
ORAI2 Q96SN7 1/20 0.39
ORAI3 Q9BRQ5 1/20 0.39
TRPV6 Q9H1D0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27603216 0.82 MAOA (0.49) CA1CA2IDO1CA9MAOA
SCHEMBL15850504 0.81 CES2 (0.52) CES2CES1CA1CA2BCL2L1
SCHEMBL931503 0.77 C1S (0.53) CYP3A4MAOB
SCHEMBL8261014 0.77 CES2 (0.48) CES2CES1CA1CA2BCL2L1
SCHEMBL13550601 0.77 CES2 (0.48) CES2CES1CA1CA2BCL2L1
SCHEMBL523255 0.77 LMNA (0.59)
SCHEMBL15372970 0.76 ATM (0.53) CES2CES1LTA4H
Iodide SCHEMBL3773658 0.75 LMNA (0.56)
Hydrochloric Acid SCHEMBL1019443 0.75 PRSS1 (0.61)
SCHEMBL3697081 0.73 CES2 (0.58) CES2CES1CA1CA2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591939-A Crystalline polyaryletherketone surface grafted carbon fiber and preparation method thereof 吉林大学 2025-03-11 CN claimed
CN-119591938-A Crystalline polyaryletherketone surface grafted carbon nano tube and preparation method thereof 吉林大学 2025-03-11 CN claimed
CN-119570113-A Crystalline polyaryletherketone surface grafted graphene and preparation method thereof 吉林大学 2025-03-07 CN claimed
CN-110841493-B Polyaryletherketone separation membrane or sulfonated polyaryletherketone separation membrane with adjustable pore diameter and preparation method thereof 吉林大学 2021-08-03 CN claimed
CN-110841493-A Polyaryletherketone separation membrane or sulfonated polyaryletherketone separation membrane with adjustable pore diameter and preparation method thereof 吉林大学 2020-02-28 CN claimed
CN-119591939-A Crystalline polyaryletherketone surface grafted carbon fiber and preparation method thereof 吉林大学 2025-03-11 CN disclosed
CN-119591938-A Crystalline polyaryletherketone surface grafted carbon nano tube and preparation method thereof 吉林大学 2025-03-11 CN disclosed
CN-119570113-A Crystalline polyaryletherketone surface grafted graphene and preparation method thereof 吉林大学 2025-03-07 CN disclosed
CN-115339112-B Three-dimensional high-heat-conductivity electromagnetic shielding polyaryletherketone composite material and preparation method and application thereof 吉林大学 2024-06-18 CN disclosed
CN-115125634-B Method for preparing high-thermal-conductivity electromagnetic shielding polyarylether composite fiber based on electrostatic spinning technology, polyarylether composite material and application 吉林大学 2023-04-07 CN disclosed
CN-115339112-A Three-dimensional high-thermal-conductivity electromagnetic shielding polyaryletherketone composite material and preparation method and application thereof 吉林大学 2022-11-15 CN disclosed
CN-115125634-A Method for preparing high-thermal-conductivity electromagnetic shielding polyarylether composite fiber based on electrostatic spinning technology, polyarylether composite material and application 吉林大学 2022-09-30 CN disclosed
EP-2508518-A1 CYCLIC POLYPHENYLENE ETHER ETHER KETONE COMPOSITION AND METHOD FOR PRODUCING THE SAME Toray Industries, Inc. (JP) 2012-10-10 EP disclosed
US-7482358-B2 Imidazoline compounds BANYU PHARMACEUTICAL CO., LTD. (JP) 2009-01-27 US disclosed
WO-2007055698-A1 IMPROVED METHOD FOR MAKING AMINO ACID CLYCOSIDES AND GLYCOPEPTIDES THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2007-05-18 WO disclosed
US-20060135559-A1 Novel imidazoline compounds MSD K.K. (JP) 2006-06-22 US disclosed
US-7064142-B2 Imidazonline compounds BANYU PHARMACEUTICAL, CO., LTD. (JP) 2006-06-20 US disclosed
EP-1264826-B1 NOVEL IMIDAZOLINE COMPOUNDS BANYU PHARMA CO LTD (JP) 2005-03-30 EP disclosed
US-20030158418-A1 Novel imidazonline compounds MSD K.K. (JP) 2003-08-21 US disclosed
EP-1264826-A1 NOVEL IMIDAZOLINE COMPOUNDS BANYU PHARMACEUTICAL CO., LTD. (JP) 2002-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060135559-A1 Novel imidazoline compounds GPR119, NPY1R, NPY2R CES2 1000/4885CES1 402/4885CA1 4286/4885
US-20030158418-A1 Novel imidazonline compounds NPY1R, NPY2R, GPR119 CES2 1239/4885CES1 556/4885CA1 4577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.