Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10865815 | 0.79 | MEN1 (0.66) | MEN1KMT2ALMNASMN1; SMN2RAB9A | |
| SCHEMBL170428 | 0.77 | MEN1 (0.68) | MEN1KMT2ALMNASMN1; SMN2RAB9A | |
| SCHEMBL30614510 | 0.77 | MEN1 (0.68) | MEN1KMT2ALMNASMN1; SMN2RAB9A | |
| SCHEMBL1926880 | 0.76 | LMNA (0.48) | LMNASMN1; SMN2NPC1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL6418353 | 0.76 | MEN1 (0.66) | MEN1KMT2ALMNASMN1; SMN2RAB9A | |
| Ethane SCHEMBL27458330 | 0.76 | MEN1 (0.66) | MEN1KMT2ALMNASMN1; SMN2RAB9A | |
| SCHEMBL5749470 | 0.75 | HPGDS (0.50) | MEN1KMT2ALMNASMN1; SMN2RAB9A | |
| SCHEMBL1927152 | 0.72 | LMNA (0.46) | MEN1KMT2ALMNASMN1; SMN2PDE10A | |
| SCHEMBL2401863 | 0.72 | MMP2 (0.59) | LMNASMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL1926708 | 0.72 | CCR1 (0.46) | MEN1KMT2ALMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | PMV PHARMACEUTICALS, INC. | 2024-04-11 | — | — | US | claimed |
| WO-2023237730-A1 | RSV INHIBITING TRIAZOLO AND SPIRO BEARING DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-12-14 | — | — | WO | claimed |
| EP-3141552-B1 | THIENOPYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE | HANMI PHARM IND CO LTD (KR) | 2019-04-17 | — | — | EP | claimed |
| WO-2012048894-A1 | HYBRID COMPOUNDS OF 4- AND 8-AMINOQUINOLINES FOR THE PROPHYLACTIC AND THERAPEUTIC TREATMENT OF MALARIA AND OTHER PARASITIC DISEASES | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2012-04-19 | — | — | WO | claimed |
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | PMV PHARMACEUTICALS, INC. | 2024-04-11 | — | — | US | disclosed |
| WO-2023237730-A1 | RSV INHIBITING TRIAZOLO AND SPIRO BEARING DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-12-14 | — | — | WO | disclosed |
| WO-2012048894-A1 | HYBRID COMPOUNDS OF 4- AND 8-AMINOQUINOLINES FOR THE PROPHYLACTIC AND THERAPEUTIC TREATMENT OF MALARIA AND OTHER PARASITIC DISEASES | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2012-04-19 | — | — | WO | disclosed |
| US-7521454-B2 | Adenine derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-04-21 | — | — | US | disclosed |
| EP-1386923-B1 | NOVEL ADENINE DERIVATIVES | DAINIPPON SUMITOMO PHARMA CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20070037832-A1 | 2-butylamino-8-hydroxy-9-(6-methyl-3-pyridylmethyl)adenine; interferon inducing activity; antiviral, antiallergic agent; immune response modulator; hepatitis B and C, asthma, atopic dermatitis | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
| US-7157465-B2 | Adenine derivatives | DAINIPPON SIMITOMO PHARMA CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |
| US-20040132748-A1 | Novel adenne derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| EP-1386923-A1 | NOVEL ADENINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132748-A1 | Novel adenne derivatives | IRF3, IFNAR1, STING1 | MEN1 4502/4885KMT2A 2518/4885LMNA 3826/4885 |
| US-20070037832-A1 | 2-butylamino-8-hydroxy-9-(6-methyl-3-pyridylmethyl)adenine; interferon inducing activity; antiviral, antiallergic agent; immune response modulator; hepatitis B and C, asthma, atopic dermatitis | IRF3, IFNAR1, IFNG | MEN1 4698/4885KMT2A 1436/4885LMNA 3680/4885 |
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | WAPL, WHR1, G3BP1 | MEN1 1607/4885KMT2A 1729/4885LMNA 4720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.