SCHEMBL447819

SCHEMBL447819

CCC(=O)OCCC(C)O

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.48
CYP19A1 P11511 1/20 0.40
GAA P10253 1/20 0.38
MAPT P10636 2/20 0.37
ADRA2A P08913 1/20 0.37
ADRA1A P35348 1/20 0.37
HTT P42858 1/20 0.36
BLM P54132 2/20 0.35
CHRNB2 P17787 3/20 0.35
CHRNA4 P43681 3/20 0.35
CHRNB4 P30926 2/20 0.35
CHRNA3 P32297 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP2C19 P33261 2/20 0.35
CYP1A2 P05177 1/20 0.35
HPGD P15428 1/20 0.35
WRN Q14191 1/20 0.35
HIF1A Q16665 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22127640 1.00 NAAA (0.48) NAAACYP19A1GAAMAPTADRA2A
SCHEMBL28154352 0.84 NAAA (0.50) NAAACYP19A1GAAADRA2AADRA1A
SCHEMBL22028559 0.84 ADRA2A (0.54) CYP19A1MAPTADRA2AADRA1ABLM
SCHEMBL126952 0.84 NAAA (0.50) NAAACYP19A1GAAHTTCHRNB2
SCHEMBL24586928 0.84 NAAA (0.50) NAAACYP19A1GAAADRA2AADRA1A
SCHEMBL23926234 0.84 MGAM (0.44) CYP19A1GAAMAPTADRA2AADRA1A
SCHEMBL21518280 0.84 NAAA (0.50) NAAACYP19A1GAAHTTBLM
SCHEMBL28572438 0.84 NAAA (0.50) NAAACYP19A1GAAHTTCHRNB2
SCHEMBL20581506 0.83 MAPT (0.47) NAAACYP19A1MAPTADRA2AADRA1A
SCHEMBL23159167 0.83 MAPT (0.47) NAAACYP19A1MAPTADRA2AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240180941-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2024-06-06 US disclosed
US-11813272-B2 Active agents and methods of their use for the treatment of metabolic disorders and nonalcoholic fatty liver disease FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2023-11-14 US disclosed
US-20210177877-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2021-06-17 US disclosed
EP-3801496-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE Flagship Pioneering Innovations V, Inc. (US) 2021-04-14 EP disclosed
EP-3801587-A1 ACYLATED CATECHIN POLYPHENOLS AND METHODS OF THEIR USE FOR THE TREATMENT OF CANCER Flagship Pioneering Innovations V, Inc. (US) 2021-04-14 EP disclosed
US-20210085640-A1 ACYLATED CATECHIN POLYPHENOLS AND METHODS OF THEIR USE FOR THE TREATMENT OF CANCER FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-03-25 US disclosed
US-10953027-B2 Active agents and methods of their use for the treatment of metabolic disorders and nonalcoholic fatty liver disease FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2021-03-23 US disclosed
US-20200197428-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE FLAGSHIP PIONEERING, INC. 2020-06-25 US disclosed
US-10391750-B2 Cover window plate and image display device including the same DONGWOO FINE-CHEM CO., LTD. (KR) 2019-08-27 US disclosed
US-20180178494-A1 COVER WINDOW PLATE AND IMAGE DISPLAY DEVICE INCLUDING THE SAME DONGWOO FINE-CHEM CO., LTD. (KR) 2018-06-28 US disclosed
US-20120270142-A1 PHOTOSENSITIVE COMPOSITION AND METHOD OF MANUFACTURING A SUBSTRATE FOR A DISPLAY DEVICE USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-10-25 US disclosed
US-20120064455-A1 PHOTORESIST COMPOSITION AND METHOD OF FORMING PATTERN USING THE SAME SAMSUNG TECHWIN CO., LTD. (KR) 2012-03-15 US disclosed
CN-1818778-A Photosensitive resin composition, thin film panel and method for manufacturing thin film panel SAMSUNG ELECTRONICS CO LTD (KR) 2006-08-16 CN disclosed
US-20060177767-A1 Photosensitive resin composition, thin film panel including a layer made from photosensitive resin composition, and method for manufacturing thin film panel SAMSUNG ELECTRONICS CO., LTD. 2006-08-10 US disclosed
CN-1266544-C Photosnesitive resin composition comprising quinonediazide sulfate ester compound DONGJIN SEMICHEM CO LTD (KR) 2006-07-26 CN disclosed
CN-1568444-A Photosnesitive resin composition comprising quinonediazide sulfate ester compound DONGJIN SEMICHEM CO LTD (KR) 2005-01-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11813272-B2 Active agents and methods of their use for the treatment of metabolic disorders and nonalcoholic fatty liver disease FABP1, PYGL, LIPC NAAA 883/4885CYP19A1 993/4885GAA 62/4885
US-20240180941-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE FABP1, PYGL, LIPC NAAA 883/4885CYP19A1 993/4885GAA 62/4885
US-20210085640-A1 ACYLATED CATECHIN POLYPHENOLS AND METHODS OF THEIR USE FOR THE TREATMENT OF CANCER ACAT2, ACAT1, FABP6 NAAA 321/4885CYP19A1 456/4885GAA 317/4885
US-20200197428-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE FABP1, PYGL, LIPC NAAA 883/4885CYP19A1 993/4885GAA 62/4885
US-20210177877-A1 ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE FABP1, PYGL, LIPC NAAA 883/4885CYP19A1 993/4885GAA 62/4885
US-10953027-B2 Active agents and methods of their use for the treatment of metabolic disorders and nonalcoholic fatty liver disease FABP1, PYGL, LIPC NAAA 883/4885CYP19A1 993/4885GAA 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.