Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.30 |
| ▸ | FEN1 | P39748 | 2/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4507666 | 0.84 | GSK3B (0.36) | SCN10A | |
| SCHEMBL4692686 | 0.84 | SCN10A (0.31) | SCN10A | |
| SCHEMBL4499049 | 0.82 | SCN10A (0.33) | SCN10A | |
| SCHEMBL13606351 | 0.82 | JAK2 (0.43) | SCN10A | |
| SCHEMBL4690562 | 0.82 | CDK2 (0.42) | — | |
| SCHEMBL13606354 | 0.81 | ALDH1A1 (0.37) | SCN10A | |
| SCHEMBL13606352 | 0.80 | SCN10A (0.31) | SCN10A | |
| SCHEMBL13606357 | 0.79 | JAK2 (0.35) | SCN10A | |
| SCHEMBL13606388 | 0.79 | CRHR1 (0.31) | — | |
| SCHEMBL13606353 | 0.78 | ADRA1A (0.32) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| EP-1718652-A2 | PYRAZOLOPYRIMIDINES FOR COMBATTING UNWANTED MICROORGANISMS | Bayer CropScience Aktiengesellschaft (DE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005082907-A2 | PYRAZOLOPYRIMIDINES FOR CONTROLLING UNDESIRED MICROORGANISMS | BAYER CROPSCIENCE AG (DE) | 2005-09-09 | — | — | WO | disclosed |
| US-20050187224-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187224-A1 | Pyrazolopyrimidines | P2RX5, P2RX4, P2RX1 | ADAM17 4736/4885ALOX5AP 2078/4885FEN1 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.