Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494475 | 0.91 | KDM4E (0.31) | — | |
| SCHEMBL4507666 | 0.86 | GSK3B (0.36) | SCN10A | |
| SCHEMBL4489875 | 0.84 | ADAM17 (0.32) | SCN10A | |
| SCHEMBL13606351 | 0.84 | JAK2 (0.43) | SCN10AJAK2 | |
| SCHEMBL4499049 | 0.84 | SCN10A (0.33) | SCN10AJAK2 | |
| SCHEMBL4690562 | 0.83 | CDK2 (0.42) | — | |
| SCHEMBL13606354 | 0.83 | ALDH1A1 (0.37) | SCN10AJAK2 | |
| SCHEMBL13606357 | 0.80 | JAK2 (0.35) | SCN10AJAK2 | |
| SCHEMBL5234861 | 0.80 | JAK2 (0.31) | JAK2 | |
| SCHEMBL13606388 | 0.80 | CRHR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694681-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2008-03-12 | — | — | EP | disclosed |
| EP-1697372-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| EP-1697372-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| US-20070197540-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20070197540-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20070197540-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20060276478-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2006-12-07 | — | — | US | disclosed |
| EP-1697372-A1 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-09-06 | — | — | EP | disclosed |
| EP-1694681-A1 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | UWW VENTURES UNLIMITED (GB) | 2006-04-27 | — | — | US | disclosed |
| WO-2005056556-A1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005056555-A1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | PRDX1, PRDX2, PRDX5 | SCN10A 4781/4885JAK2 2937/4885 |
| US-20070197540-A1 | Pyrazolopyrimidines | QDPR, Q6ZSR9, RPLP2 | SCN10A 4781/4885JAK2 877/4885 |
| US-20060276478-A1 | Pyrazolopyrimidines | Q6ZSR9, RPLP2, DPYD | SCN10A 4766/4885JAK2 1619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.