Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490991 | 0.89 | MGAM (0.50) | MGAMGAASIMGAM2CA2 | |
| SCHEMBL27994610 | 0.81 | CA2 (0.39) | MGAMGAASIMGAM2CA2 | |
| Butane SCHEMBL788832 | 0.80 | MGAM (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL37772 | 0.79 | LDHA (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL26462636 | 0.77 | MGAM (0.48) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL12044965 | 0.76 | CA2 (0.38) | CA2CA1ALDH1A1TSHRUSP2 | |
| Potassium SCHEMBL29692205 | 0.75 | GAA (0.70) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7450805 | 0.75 | USP2 (0.50) | MGAMGAASIMGAM2CA2 | |
| Ethylene SCHEMBL3568811 | 0.74 | LDHA (0.44) | MGAMGAASIMGAM2TSHR | |
| Ethylene SCHEMBL11358576 | 0.74 | LDHA (0.44) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553989-B2 | Malonic acid monoesters and process for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-30 | — | — | US | claimed |
| US-20050272950-A1 | Malonic acid monoesters and process for producing the same | MEIJI SEIKA KAISHA LTD. (JP) | 2005-12-08 | — | — | US | claimed |
| EP-1561748-A1 | MALONIC ACID MONOESTERS AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2005-08-10 | — | — | EP | claimed |
| US-7553989-B2 | Malonic acid monoesters and process for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20050272950-A1 | Malonic acid monoesters and process for producing the same | MEIJI SEIKA KAISHA LTD. (JP) | 2005-12-08 | — | — | US | disclosed |
| EP-1561748-A1 | MALONIC ACID MONOESTERS AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2005-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272950-A1 | Malonic acid monoesters and process for producing the same | ME1, SI, ME3 | MGAM 4/4885GAA 12/4885SI 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.