SCHEMBL4491300

SCHEMBL4491300

CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1COC1CCOC1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ATF4 P18848 1/20 0.32
MDM2 Q00987 3/20 0.30
TP53 P04637 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570217 0.87 SCN9A (0.38)
SCHEMBL4509954 0.85 ATF4 (0.35) ATF4
SCHEMBL4504247 0.83 MDM2 (0.30) ATF4MDM2TP53
SCHEMBL12269385 0.81 ALDH1A1 (0.33)
SCHEMBL12770863 0.80 HPD (0.36)
SCHEMBL118936 0.79 OXTR (0.36)
SCHEMBL14668722 0.78 HPD (0.34)
SCHEMBL12770865 0.78 OXTR (0.34)
SCHEMBL6571078 0.77 HRH3 (0.34)
SCHEMBL4906207 0.77 HPD (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569519-B2 Substituted benzoyl derivatives as herbicides BAYER CROPSCIENCE AG (DE) 2009-08-04 US disclosed
US-20070244008-A1 Substituted benzoyl derivatives as herbicides BAYER CROPSCIENCE GMBH (DE) 2007-10-18 US disclosed
EP-1585742-B1 SUBSTITUTED BENZOYL DERIVATIVES USES AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2007-08-08 EP disclosed
EP-1585742-A1 SUBSTITUTED BENZOYL DERIVATIVES USES AS HERBICIDES Bayer CropScience GmbH (DE) 2005-10-19 EP disclosed
US-20040167029-A1 Substituted benzoyl derivatives as herbicides BAYER CROPSCIENCE GMBH (DE) 2004-08-26 US disclosed
WO-2004063187-A1 SUBSTITUTED BENZOYL DERIVATIVES USES AS HERBICIDES BAYER CROPSCIENCE GMBH (DE) 2004-07-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244008-A1 Substituted benzoyl derivatives as herbicides SQOR, CBR3, DDT ATF4 3575/4885MDM2 191/4885TP53 2930/4885
US-20040167029-A1 Substituted benzoyl derivatives as herbicides DDT, SQOR, CBR3 ATF4 3857/4885MDM2 299/4885TP53 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.