Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495798 | 0.86 | ERN1 (0.46) | ALDH1A1RAB9AKDM5BERN1SMN1; SMN2 | |
| SCHEMBL4491747 | 0.78 | MEN1 (0.40) | ALDH1A1RAB9APKMSMN1; SMN2TDP1 | |
| SCHEMBL4488479 | 0.75 | ALDH1A1 (0.44) | ALDH1A1RAB9AERN1RAF1KDM4E | |
| SCHEMBL4492959 | 0.73 | CA12 (0.41) | ALDH1A1RAB9AERN1KDM4ELMNA | |
| SCHEMBL4497716 | 0.71 | BTK (0.41) | — | |
| SCHEMBL4490045 | 0.71 | PPARG (0.42) | ALDH1A1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4488655 | 0.70 | KDM4E (0.36) | ALDH1A1KDM5BERN1KDM4ELMNA | |
| SCHEMBL4504198 | 0.70 | LDHA (0.38) | ALDH1A1KDM5BKDM4ETLR9TLR8 | |
| SCHEMBL4494581 | 0.69 | ESR1 (0.38) | ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4492341 | 0.69 | LDHA (0.36) | ALDH1A1KDM4ENPC1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |