Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494581 | 0.90 | ESR1 (0.38) | ALDH1A1MEN1KMT2ALDHARAB9A | |
| SCHEMBL4485738 | 0.89 | MTNR1A (0.41) | ALDH1A1KMT2AHPGD | |
| SCHEMBL4485668 | 0.85 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL4504906 | 0.83 | MEN1 (0.45) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL4482572 | 0.83 | PPARG (0.41) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL4559834 | 0.81 | PPARG (0.41) | PPARGPPARAALDH1A1MAPTMEN1 | |
| SCHEMBL4492334 | 0.79 | TAAR1 (0.36) | MEN1KMT2ACYP1A2HPGDLDHA | |
| SCHEMBL4504872 | 0.79 | LDHA (0.38) | PPARGPPARAMEN1KMT2ALDHA | |
| SCHEMBL4481909 | 0.77 | KDM4E (0.40) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4485206 | 0.77 | ALDH1A1 (0.32) | ALDH1A1MAPTMEN1GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |