Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR39 | O43194 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499369 | 0.84 | RAB9A (0.37) | HSD11B1MEN1RAB9AKMT2A | |
| SCHEMBL4494475 | 0.81 | KDM4E (0.31) | MEN1KMT2A | |
| SCHEMBL4510395 | 0.77 | HSD11B1 (0.34) | HSD11B1MEN1RAB9AKMT2A | |
| SCHEMBL14360022 | 0.76 | ALDH1A1 (0.37) | MEN1KMT2A | |
| SCHEMBL13606353 | 0.72 | ADRA1A (0.32) | RAB9AGPR39 | |
| SCHEMBL4507666 | 0.72 | GSK3B (0.36) | — | |
| SCHEMBL4692686 | 0.72 | SCN10A (0.31) | — | |
| SCHEMBL13606358 | 0.72 | NISCH (0.33) | — | |
| SCHEMBL13606355 | 0.71 | — | — | |
| SCHEMBL13606359 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| US-20050187224-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187224-A1 | Pyrazolopyrimidines | P2RX5, P2RX4, P2RX1 | HSD11B1 3768/4885MEN1 2381/4885RAB9A 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.