Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.51 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
| ▸ | CYCS | P99999 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4753685 | 0.99 | TERT (0.53) | TERTTOP1CYCS | |
| SCHEMBL453031 | 0.99 | TERT (0.52) | TERTTOP1CYCSENPP2 | |
| SCHEMBL29935687 | 0.97 | TERT (0.51) | TERTTOP1CYCSENPP2 | |
| Hydrochloric Acid SCHEMBL4753666 | 0.96 | TERT (0.50) | TERTTOP1CYCSENPP2 | |
| SCHEMBL450264 | 0.89 | TERT (0.48) | TERTTOP1CYCSENPP2 | |
| SCHEMBL452379 | 0.86 | TERT (0.46) | TERTTOP1 | |
| SCHEMBL6007193 | 0.85 | STAT3 (0.49) | TERT | |
| SCHEMBL30096016 | 0.84 | NPC1 (0.45) | TERT | |
| SCHEMBL452116 | 0.84 | NPC1 (0.45) | TERT | |
| SCHEMBL451943 | 0.84 | NPC1 (0.45) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113956-A1 | Substituted Porphyrins | FRIDOVICH IRWIN | 2008-05-15 | — | — | US | disclosed |
| US-20070179124-A1 | Substituted Porphyrins | FRIDOVICH IRWIN | 2007-08-02 | — | — | US | disclosed |
| US-20060074062-A1 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2006-04-06 | — | — | US | disclosed |
| US-6916799-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2005-07-12 | — | — | US | disclosed |
| EP-1045851-B1 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2003-04-23 | — | — | EP | disclosed |
| US-20020042407-A1 | Antiinflammatory agents; respiratory system disorders | DUKE UNIVERSITY | 2002-04-11 | — | — | US | disclosed |
| EP-1045851-A4 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2001-05-09 | — | — | EP | disclosed |
| EP-1045851-A1 | SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY (US) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999023097-A1 | SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY (US) | 1999-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113956-A1 | Substituted Porphyrins | PPOX, GPX4, PRDX5 | TERT 821/4885TOP1 4291/4885CYCS 76/4885 |
| US-20070179124-A1 | Substituted Porphyrins | PPOX, GPX4, PRDX5 | TERT 821/4885TOP1 4291/4885CYCS 76/4885 |
| US-20020042407-A1 | Antiinflammatory agents; respiratory system disorders | LPO, PRDX5, MPO | TERT 3237/4885TOP1 4338/4885CYCS 265/4885 |
| US-20060074062-A1 | Substituted porphyrins | PPOX, GPX4, PRDX5 | TERT 821/4885TOP1 4291/4885CYCS 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.