Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 3/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261956 | 0.85 | ALDH1A1 (0.48) | CHKACSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL6827498 | 0.76 | MAPT (0.38) | ACHEMAPTMITFKDM4ENPC1 | |
| SCHEMBL2795974 | 0.74 | CYP2A6 (0.44) | TSHRMAPTMITFLMNACYP1A2 | |
| SCHEMBL1770982 | 0.74 | MAPT (0.39) | ACHEALDH1A1MAPTMITFKDM4E | |
| SCHEMBL13829247 | 0.74 | RAB9A (0.50) | CHKAACHEMAPTHTTRAB9A | |
| SCHEMBL5784218 | 0.74 | MAPT (0.53) | ACHEALDH1A1MAPTMITFKDM4E | |
| SCHEMBL7155648 | 0.74 | MITF (0.37) | ACHEMAPTMITFLMNAHTT | |
| SCHEMBL1193736 | 0.74 | IDO1 (0.44) | CSNK2A2CSNK2BCSNK2A1ALDH1A1CYP3A4 | |
| SCHEMBL10647924 | 0.74 | MAPT (0.38) | CHKAACHEALDH1A1TDP1MAPT | |
| SCHEMBL15313372 | 0.71 | ATM (0.44) | ALDH1A1TSHRHSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200345737-A1 | SYK KINASE INHIBITORS AS TREATMENT FOR MALARIA | PURDUE RESEARCH FOUNDATION | 2020-11-05 | — | — | US | claimed |
| EP-2234642-B1 | METHOD OF INCREASING IMMUNOLOGICAL EFFECT | IRX THERAPEUTICS INC (US) | 2017-09-27 | — | — | EP | claimed |
| EP-1998811-B1 | IMMUNOTHERAPY FOR IMMUNE SUPPRESSED PATIENTS | IRX THERAPEUTICS INC (US) | 2012-10-17 | — | — | EP | claimed |
| EP-1558254-B1 | USE OF 4-AMINOQUINOLINES COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS OF THE EYE | RAUT RAJEEV (IN) | 2010-12-15 | — | — | EP | claimed |
| US-7731945-B2 | Administering an exogenous antigen and an adjuvant of a NCM+thymosin alpha 1; inducing production of naive T cells and restoring T cell immune response; treating a cancer in a severely immune suppressed patient | IMMUNO-RX, INC. (US) | 2010-06-08 | — | — | US | claimed |
| EP-1558254-A2 | A PROCESS FOR PREPARING PHARMACEUTICAL COMPOSITIONS CONTAINING 4-AMINOQUINOLINES COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS OF THE EYE, COMPOSITIONS RESULTING THEREFROM | Raut, Rajeev (IN) | 2005-08-03 | — | — | EP | claimed |
| EP-0789588-B1 | METHOD FOR MAKING A MEDICAMENT FOR TREATING SECONDARY IMMUNODEFICIENCY | UNIV SOUTH FLORIDA (US) | 2005-01-19 | — | — | EP | claimed |
| WO-2003097025-A2 | A PROCESS FOR PREPARING PHARMACEUTICAL COMPOSITIONS CONTAINING 4-AMINOQUINOLINES COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS OF THE EYE AND COMPOSITIONS RESULTING THEREFROM | RAUT RAJEEV (IN) | 2003-11-27 | — | — | WO | claimed |
| US-20030216431-A1 | Ophthalmic pharmaceutical compositions and methods for treating ocular inflammation | RAUT RAJEEV (IN) | 2003-11-20 | — | — | US | claimed |
| EP-0789588-A4 | METHOD FOR MAKING A MEDICAMENT FOR TREATING SECONDARY IMMUNODEFICIENCY | UNIV SOUTH FLORIDA (US) | 2001-11-28 | — | — | EP | claimed |
| US-5698194-A | CYTOKINE MIXTURE CONTAINING INTERLEUKINS | UNIVERSITY OF SOUTH FLORIDA (US) | 1997-12-16 | — | — | US | claimed |
| EP-0789588-A1 | METHOD FOR MAKING A MEDICAMENT FOR TREATING SECONDARY IMMUNODEFICIENCY | UNIVERSITY OF SOUTH FLORIDA (US) | 1997-08-20 | — | — | EP | claimed |
| WO-1996015808-A1 | METHOD FOR MAKING A MEDICAMENT FOR TREATING SECONDARY IMMUNODEFICIENCY | UNIVERSITY OF SOUTH FLORIDA (US) | 1996-05-30 | — | — | WO | claimed |
| US-20250099488-A1 | ANTI-PARASITE COMPOUNDS | AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2025-03-27 | — | — | US | disclosed |
| EP-4469058-A1 | ANTI-PARASITE COMPOUNDS | Australian National University (AU) | 2024-12-04 | — | — | EP | disclosed |
| CN-114989082-B | Efficient preparation method of hydroxychloroquine based on synergistic catalysis of I-valent copper compound and trisubstituted phosphine | 华东理工大学 | 2024-06-21 | — | — | CN | disclosed |
| WO-1996015808-A1 | METHOD FOR MAKING A MEDICAMENT FOR TREATING SECONDARY IMMUNODEFICIENCY | UNIVERSITY OF SOUTH FLORIDA (US) | 1996-05-30 | — | — | WO | disclosed |
| US-4767698-A | PHOTOSTABILITY, HEAT RESISTANCE | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| US-4057633-A | ANTIANXIETY, HYPOTENSIVE | THE UPJOHN COMPANY (US) | 1977-11-08 | — | — | US | disclosed |
| US-3992382-A | HYPERTENSION AND ANXIETY TREATMENT | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250099488-A1 | ANTI-PARASITE COMPOUNDS | TUBA3C, CFAP20, CFAP410 | CHKA 1911/4885CSNK2A2 4158/4885CSNK2B 4305/4885 |
| US-20030216431-A1 | Ophthalmic pharmaceutical compositions and methods for treating ocular inflammation | IL5, IL1B, IL4 | CHKA 846/4885CSNK2A2 598/4885CSNK2B 647/4885 |
| US-20200345737-A1 | SYK KINASE INHIBITORS AS TREATMENT FOR MALARIA | SYK, BTK, MERTK | CHKA 51/4885CSNK2A2 950/4885CSNK2B 1131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.