SCHEMBL4510197

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13674485	1.00	OPRM1 (0.39)	OPRM1OPRD1OPRK1HTR1ASLC6A4
	SCHEMBL4525019	0.90	FFAR4 (0.41)	HTR1ASLC6A4FFAR4HSD11B1HTR2A
	SCHEMBL4515440	0.89	FFAR4 (0.37)	OPRM1OPRD1OPRK1HTR1ASLC6A4
	SCHEMBL4505225	0.89	HSP90AA1 (0.39)	HTR1ASLC6A4HSD11B1ALDH1A1
	SCHEMBL4525933	0.89	HSD11B1 (0.41)	OPRM1OPRD1OPRK1BTKHSD11B1
	SCHEMBL4514955	0.89	S1PR1 (0.40)	OPRM1OPRD1OPRK1HTR1ASLC6A4
	SCHEMBL4509399	0.89	MCL1 (0.39)	FFAR4HSD11B1ALDH1A1
	SCHEMBL13674510	0.89	ALDH1A1 (0.38)	BTKP2RX7ALDH1A1MAPT
	SCHEMBL13674552	0.88	ACVRL1 (0.36)	OPRM1OPRD1OPRK1HTR1ASLC6A4
	SCHEMBL3001587	0.88	P2RX7 (0.42)	HSD11B1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.