SCHEMBL45127

SCHEMBL45127

CC(C)(Br)c1cc(C(C)(C)Br)cc(C(C)(C)Br)c1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
RECQL P46063 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10540685 0.89 GABRA1 (0.55) GABRA1GABRB2ALDH1A1HPGDALOX15
SCHEMBL2241265 0.79 ESR1 (0.46) GABRA1GABRB2ALDH1A1CYP3A4ALOX15
SCHEMBL9602565 0.77 TSHR (0.47) ALDH1A1CYP3A4TSHR
SCHEMBL9132402 0.73 ALDH1A1 (0.58) ALDH1A1CYP3A4ESR1
SCHEMBL7203019 0.73 KIF11 (0.52) GABRA1GABRB2ALDH1A1CYP3A4HPGD
SCHEMBL93161 0.70 GABRA1 (0.69) GABRA1GABRB2ALDH1A1HPGDALOX15
SCHEMBL642315 0.69 TAAR1 (0.57) ALDH1A1CYP3A4ALOX15TSHRHIF1A
SCHEMBL8712101 0.69 TSHR (0.52) ALDH1A1TSHR
SCHEMBL677817 0.67 ALDH1A1 (0.53) ALDH1A1TSHR
SCHEMBL17273467 0.67 TSHR (0.67) ALDH1A1TSHRALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106146709-A Cationic polymerization method 中国石油化工股份有限公司 2016-11-23 CN claimed
CN-106146705-A Preparation method of halogenated polymer 中国石油化工股份有限公司 2016-11-23 CN claimed
CN-106146706-A Cationic polymerization method 中国石油化工股份有限公司 2016-11-23 CN claimed
CN-106146707-A Preparation method of halogenated polymer 中国石油化工股份有限公司 2016-11-23 CN claimed
US-11795247-B2 Polyolefin dispersants and methods of making and using thereof THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-24 US disclosed
US-11274181-B2 Polyimide dispersants and methods of making and using thereof CHEVRON ORONITE COMPANY LLC (US) 2022-03-15 US disclosed
US-20210189030-A1 Polyolefin Dispersants and Methods of Making and Using Thereof UNIVERSITY OF SOUTHERN MISSISSIPPI 2021-06-24 US disclosed
US-10875946-B2 Polyolefin dispersants and methods of making and using thereof CHEVRON ORONITE COMPANY LLC (US) 2020-12-29 US disclosed
EP-3684842-A1 POLYOLEFIN DISPERSANTS AND METHODS OF MAKING AND USING THEREOF Chevron Oronite Company LLC (US) 2020-07-29 EP disclosed
EP-3684894-A1 POLYIMIDE DISPERSANTS AND METHODS OF MAKING AND USING THEREOF Chevron Oronite Company LLC (US) 2020-07-29 EP disclosed
US-20190284314-A1 Polyolefin Dispersants and Methods of Making and Using Thereof CHEVRON ORONITE COMPANY LLC. 2019-09-19 US disclosed
WO-2019055984-A1 POLYIMIDE DISPERSANTS AND METHODS OF MAKING AND USING THEREOF CHEVRON ORONITE COMPANY LLC (US) 2019-03-21 WO disclosed
WO-2011159468-A2 VINYL ETHER END-FUNCTIONALIZED POLYOLEFINS THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-12-22 WO disclosed
US-20110306745-A1 VINYL ETHER END-FUNCTIONALIZED POLYOLEFINS UNIVERSITY OF SOUTHERN MISSISSIPPI 2011-12-15 US disclosed
EP-2387592-A2 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES The University of Southern Mississippi (US) 2011-11-23 EP disclosed
US-8040728-B2 Semiconductor integrated circuit SEIKO EPSON CORPORATION (JP) 2011-10-18 US disclosed
US-20110028681-A1 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS THE UNIVERSITY OF SOUTHERN MISSISSIPPI 2011-02-03 US disclosed
WO-2011014665-A2 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-02-03 WO disclosed
US-20100184918-A1 Functionalization of Polyolefins with Phenoxy Derivatives UNIVERSITY OF SOUTHERN MISSISSIPPI 2010-07-22 US disclosed
WO-2010083181-A2 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2010-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028681-A1 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS RXFP3, HCAR3, LPAR3 GABRA1 2462/4885GABRB2 2474/4885ALDH1A1 2695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.