Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27923968 | 0.77 | DNM1 (0.38) | DNM1ALDH1A1TDP1 | |
| SCHEMBL1569375 | 0.75 | DNM1 (0.36) | DNM1ALDH1A1TDP1 | |
| SCHEMBL28981796 | 0.71 | DNM1 (0.33) | DNM1ALDH1A1TDP1 | |
| SCHEMBL28216210 | 0.70 | DNM1 (0.32) | DNM1 | |
| SCHEMBL27751696 | 0.70 | DNM1 (0.32) | DNM1 | |
| SCHEMBL3749524 | 0.68 | LMNA (0.41) | DNM1ALDH1A1 | |
| SCHEMBL708796 | 0.68 | TSHR (0.38) | ALDH1A1TDP1 | |
| SCHEMBL446925 | 0.68 | — | — | |
| SCHEMBL14760415 | 0.67 | ALDH1A1 (0.34) | DNM1ALDH1A1TDP1 | |
| SCHEMBL6841669 | 0.67 | DNM1 (0.33) | DNM1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009750-A1 | PHOSPHONATE NUCLEOSIDES USEFUL AS ACTIVE INGREDIENTS IN PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS, AND INTERMEDIATES FOR THEIR PRODUCTION | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2016-01-14 | — | — | US | claimed |
| WO-2012107532-A1 | 4-AMINOALCOHOLQUINOLINE DERIVATIVES, ENANTIOSELECTIVE SYNTHESIS METHODS AND THE USE THEREOF | Université de Picardie Jules Verne (FR) | 2012-08-16 | — | — | WO | claimed |
| EP-2487157-A1 | Enantioselective synthesis method of 4-aminoalcoholquinoline derivatives and the use | Université de Picardie Jules Verne (FR) | 2012-08-15 | — | — | EP | claimed |
| CN-114787139-A | Processes and intermediates for preparing MCL1 inhibitors | 吉利德科学公司 | 2022-07-22 | — | — | CN | disclosed |
| US-11220482-B2 | Aminopyridinemethanol compounds and their use | UNIVERSITE AMIENS PICARDIE JULES VERNE (FR) | 2022-01-11 | — | — | US | disclosed |
| CN-111954676-A | 2'3' -Cyclic dinucleotides | 捷克共和国有机化学与生物化学研究所 | 2020-11-17 | — | — | CN | disclosed |
| CN-111954675-A | 3'3' -Cyclic dinucleotides | 捷克共和国有机化学与生物化学研究所 | 2020-11-17 | — | — | CN | disclosed |
| EP-3704093-A1 | NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE | Université Amiens Picardie Jules Verne (FR) | 2020-09-09 | — | — | EP | disclosed |
| US-20200255379-A1 | NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE | UNIV AMIENS PICARDIE JULES VERNE (FR) | 2020-08-13 | — | — | US | disclosed |
| WO-2012107532-A1 | 4-AMINOALCOHOLQUINOLINE DERIVATIVES, ENANTIOSELECTIVE SYNTHESIS METHODS AND THE USE THEREOF | Université de Picardie Jules Verne (FR) | 2012-08-16 | — | — | WO | disclosed |
| EP-2487157-A1 | Enantioselective synthesis method of 4-aminoalcoholquinoline derivatives and the use | Université de Picardie Jules Verne (FR) | 2012-08-15 | — | — | EP | disclosed |
| US-20090258883-A1 | 1H-Indole-Pyridinecarboxamide and 1H-Indole-Piperidinecarboxamide Compounds | LES LABORATOIRES SERVIER (FR) | 2009-10-15 | — | — | US | disclosed |
| EP-0685234-B1 | DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER | NIPPON SHINYAKU CO LTD (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-6020317-A | Glycerol derivative, device and pharmaceutical composition | NIPPON SHINYAKU CO. LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0685457-B1 | GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU CO LTD (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5705188-A | LIPID MIXTURE, ANTITUMOR AGENTS | NIPPON SHINYAKU COMPANY, LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0685457-A1 | GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-12-06 | — | — | EP | disclosed |
| EP-0685234-A1 | DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-12-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11220482-B2 | Aminopyridinemethanol compounds and their use | QDPR, PNMT, CYP3A43 | DNM1 495/4885ALDH1A1 472/4885TDP1 2290/4885 |
| US-20200255379-A1 | NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE | QDPR, PNMT, CYP3A43 | DNM1 415/4885ALDH1A1 736/4885TDP1 2683/4885 |
| US-20090258883-A1 | 1H-Indole-Pyridinecarboxamide and 1H-Indole-Piperidinecarboxamide Compounds | IDO1, AHR, IDO2 | DNM1 3161/4885ALDH1A1 370/4885TDP1 2926/4885 |
| US-20160009750-A1 | PHOSPHONATE NUCLEOSIDES USEFUL AS ACTIVE INGREDIENTS IN PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS, AND INTERMEDIATES FOR THEIR PRODUCTION | PNP, NUDT1, TYMP | DNM1 2987/4885ALDH1A1 2698/4885TDP1 1373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.