Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.79 |
| ▸ | CES1 | P23141 | 2/20 | 0.79 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15180847 | 1.00 | CES2 (0.79) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL3169331 | 0.89 | CES2 (1.00) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL7604854 | 0.84 | L3MBTL1 (0.56) | CES2CES1L3MBTL1PKMTSHR | |
| SCHEMBL29665004 | 0.82 | CES2 (0.71) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL28396 | 0.82 | CES2 (0.71) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL13950378 | 0.82 | CES2 (0.71) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL28788147 | 0.81 | CES2 (0.63) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL29019528 | 0.81 | CES2 (0.63) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL22718375 | 0.81 | CES2 (0.76) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL3650973 | 0.81 | CES2 (0.76) | CES2CES1PARP1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109575032-A | The method of level-one amine guiding building 6- (3- fluorophenyl) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-04-05 | — | — | CN | claimed |
| EP-0975584-B1 | SYNTHESIS AND USE OF ALPHA-KETOAMIDE DERIVATIVES AND ARRAYS | ARQULE INC (US) | 2002-09-25 | — | — | EP | claimed |
| JP-60215647-A | — | — | None | — | — | JP | disclosed |
| EP-4095162-A1 | APPLICATION OF AND PREPARATION METHOD FOR CATIONIC POLYMER MODIFIED BY FLUORINE-CONTAINING COMPOUND AS DRUG CARRIER | Soochow University (CN) | 2022-11-30 | — | — | EP | disclosed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-109575032-A | The method of level-one amine guiding building 6- (3- fluorophenyl) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-109575032-A | The method of level-one amine guiding building 6- (3- fluorophenyl) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-108017635-A | A kind of method of successive reaction synthesizing aryl benzoquinolizine ketone compounds | 黑龙江大学 | 2018-05-11 | — | — | CN | disclosed |
| US-20170296681-A1 | COMPOSITIONS AND METHODS FOR IMAGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-10-19 | — | — | US | disclosed |
| EP-2661428-B1 | QUINOXALINES AND AZA-QUINOXALINES AS CRTH2 RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2017-06-07 | — | — | EP | disclosed |
| EP-2661428-B1 | QUINOXALINES AND AZA-QUINOXALINES AS CRTH2 RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2017-06-07 | — | — | EP | disclosed |
| WO-2012087861-A1 | QUINOXALINES AND AZA-QUINOXALINES AS CRTH2 RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20090306062-A1 | 2,5-Disubstituted Piperidines | NOVARTIS AG (CH) | 2009-12-10 | — | — | US | disclosed |
| CN-1188471-A | 1,4-disubstituted piepridine derivatives | BANYU PHARMA CO LTD (JP) | 1998-07-22 | — | — | CN | disclosed |
| US-5334726-A | Controlling weeds | ROHM AND HAAS COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| US-5120347-A | Pre and postemergence | ROHM AND HAAS COMPANY (US) | 1992-06-09 | — | — | US | disclosed |
| US-4801708-A | FOR AGRICULTURAL USE | CIBA-GEIGY CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0150677-B1 | HERBICIDAL AND INSECTICIDAL TRIAZINONES | CIBA-GEIGY AG (CH) | 1989-01-18 | — | — | EP | disclosed |
| JP-S60215647-A | PREPARATION OF AROMATIC ALPHA-HYDROXY ACID | AJINOMOTO CO INC | 1985-10-29 | — | — | JP | disclosed |
| EP-0150677-A1 | Herbicidal and insecticidal triazinones | CIBA-GEIGY AG (CH) | 1985-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170296681-A1 | COMPOSITIONS AND METHODS FOR IMAGING | GPX4, PRDX5, PRDX2 | CES2 1320/4885CES1 1166/4885PARP1 3012/4885 |
| US-20090306062-A1 | 2,5-Disubstituted Piperidines | REN, AGTR1, AGTR2 | CES2 247/4885CES1 328/4885PARP1 1566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.