Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188766 | 0.82 | CYP1A2 (0.45) | CYP3A4CYP1A2HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL3180881 | 0.76 | HSD17B10 (0.49) | CYP3A4CYP1A2HSD17B10SMN1; SMN2GLA | |
| SCHEMBL13403037 | 0.74 | BAZ2B (0.37) | HSD17B10HPGDGLATHRB | |
| SCHEMBL29025896 | 0.70 | CYP1A2 (0.61) | CYP3A4CYP1A2HSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL7379657 | 0.69 | CYP1A2 (0.45) | CYP3A4CYP1A2HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL10686284 | 0.65 | NOTUM (0.45) | CYP3A4CYP1A2HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL4519599 | 0.65 | ALDH1A1 (0.61) | SMN1; SMN2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL8145766 | 0.64 | CYP1A2 (0.67) | CYP3A4CYP1A2HSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL17788 | 0.64 | MAPT (0.43) | CYP3A4CYP1A2HSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL2279251 | 0.64 | KDM4E (0.62) | CYP3A4SMN1; SMN2MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143368-A1 | Use of Cinnamoyl Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-04 | — | — | US | disclosed |
| EP-1857104-A1 | USE OF CINNAMOYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143368-A1 | Use of Cinnamoyl Compound | COL2A1, COL1A1, SMAD2 | CYP3A4 4053/4885CYP1A2 3090/4885HSD17B10 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.