SCHEMBL4519599

SCHEMBL4519599

CC(=O)c1c(C)cc(C)[nH]c1=O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
SMN1; SMN2 Q16637 6/20 0.51
LMNA P02545 6/20 0.51
HTT P42858 4/20 0.51
NPSR1 Q6W5P4 3/20 0.51
MEN1 O00255 5/20 0.51
KMT2A Q03164 5/20 0.51
PKM P14618 1/20 0.50
MAPK1 P28482 1/20 0.50
MAPT P10636 4/20 0.49
GAA P10253 1/20 0.49
KDM4E B2RXH2 2/20 0.47
POLB P06746 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PAX8 Q06710 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3528049 0.83 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2LMNAHTTNPSR1
SCHEMBL2279251 0.82 KDM4E (0.62) ALDH1A1SMN1; SMN2LMNAHTTNPSR1
SCHEMBL21543996 0.82 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2LMNAHTTNPSR1
SCHEMBL15782798 0.79 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2LMNAHTTNPSR1
SCHEMBL679558 0.76 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2LMNAHTTNPSR1
SCHEMBL7379657 0.75 CYP1A2 (0.45) ALDH1A1SMN1; SMN2LMNAMAPTGAA
SCHEMBL3188766 0.75 CYP1A2 (0.45) ALDH1A1SMN1; SMN2MAPTGAAKDM4E
SCHEMBL24079174 0.72 KDM4E (0.54) ALDH1A1SMN1; SMN2LMNAHTTNPSR1
SCHEMBL3728873 0.71 CYP1A2 (0.40) ALDH1A1SMN1; SMN2LMNAHTTNPSR1
SCHEMBL2551804 0.71 MAPK1 (0.50) ALDH1A1SMN1; SMN2LMNAHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4172153-A1 SUBSTITUTED HETEROARYLOXYPYRIDINES, THE SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS Bayer Aktiengesellschaft (DE) 2023-05-03 EP disclosed
CN-115996919-A Substituted heteroaryloxy pyridines, salts thereof and their use as herbicides 拜耳公司 2023-04-21 CN disclosed
EP-1538145-B1 PROCESS FOR PRODUCTION OF PHENOXY-SUBSTITUTED 2-PYRIDONE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2016-02-17 EP disclosed
US-20090143368-A1 Use of Cinnamoyl Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 US disclosed
EP-1857104-A1 USE OF CINNAMOYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-11-21 EP disclosed
US-7189855-B2 Process for production of phenoxy-substituted 2-pyridone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-13 US disclosed
US-7189855-B2 Process for production of phenoxy-substituted 2-pyridone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-13 US disclosed
US-7189855-B2 Process for production of phenoxy-substituted 2-pyridone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-13 US disclosed
US-20050154210-A1 Process for production of phenoxy-substituted 2-pyridone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-14 US disclosed
EP-1538145-A1 PROCESS FOR PRODUCTION OF PHENOXY-SUBSTITUTED 2-PYRIDONE COMPOUNDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed
US-4559347-A 3-Substituted-5-alkyl-1,6-naphthyridin-2(1H)-ones, cardiotonic use and preparation thereof STERLING DRUG INC. (US) 1985-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050154210-A1 Process for production of phenoxy-substituted 2-pyridone compounds PDK2, ME1, PDXK ALDH1A1 57/4885SMN1; SMN2 4015/4885LMNA 2778/4885
US-20090143368-A1 Use of Cinnamoyl Compound COL2A1, COL1A1, SMAD2 ALDH1A1 749/4885SMN1; SMN2 4490/4885LMNA 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.