Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.69 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 7/20 | 0.53 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146151 | 0.80 | PTPN2 (0.51) | FBP1PTPN2PTPN1PTPN5AGPAT2 | |
| SCHEMBL4515469 | 0.78 | TP53 (0.76) | AGPAT2MAPTTP53POLBBLM | |
| SCHEMBL616005 | 0.77 | FBP1 (0.65) | FBP1PTPN2PTPN1PTPN5MAPT | |
| SCHEMBL4509303 | 0.74 | AGPAT2 (0.59) | PTPN2PTPN1PTPN5AGPAT2MAPT | |
| SCHEMBL23752330 | 0.73 | FBP1 (1.00) | FBP1 | |
| SCHEMBL5341294 | 0.72 | ALPL (0.55) | FBP1MAPTTP53 | |
| SCHEMBL4512765 | 0.71 | MAPT (0.90) | MAPTXBP1HIF1ATP53POLB | |
| SCHEMBL18460773 | 0.71 | AGPAT2 (0.77) | AGPAT2MAPTTP53 | |
| SCHEMBL617755 | 0.70 | FBP1 (0.65) | FBP1MAPTTP53POLB | |
| SCHEMBL31701025 | 0.70 | PTPN1 (1.00) | PTPN2PTPN1PTPN5HSPD1HSPE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | FBP1 362/4885PTPN2 1921/4885PTPN1 1997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.