Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491737 | 0.79 | USP2 (0.51) | L3MBTL1ALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL6213726 | 0.75 | ALDH1A1 (0.54) | L3MBTL1TSHRALDH1A1MAPTMAPK1 | |
| SCHEMBL4505557 | 0.73 | HSD17B10 (0.56) | ALDH1A1MAPTPOLBHPGDMEN1 | |
| SCHEMBL22408524 | 0.73 | TSHR (0.47) | L3MBTL1TSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4506634 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MAPTSMN1; SMN2HPGDMEN1 | |
| SCHEMBL28552164 | 0.71 | RAB9A (0.45) | L3MBTL1ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8810278 | 0.71 | POLB (0.49) | ALDH1A1MAPTMAPK1SMN1; SMN2POLB | |
| SCHEMBL6031540 | 0.68 | SMN1; SMN2 (0.58) | L3MBTL1ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6327886 | 0.68 | MAPT (0.49) | L3MBTL1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL4214095 | 0.68 | LMNA (0.65) | L3MBTL1TSHRALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560547-B2 | Hydroxyalkyl cyclic diamine compounds | KOWA CO., LTD. (JP) | 2009-07-14 | — | — | US | disclosed |
| US-20070088159-A1 | HYDROXYALKYL CYCLIC DIAMINE COMPOUNDS | KOWA CO., LTD. (JP) | 2007-04-19 | — | — | US | disclosed |
| US-7176306-B2 | Hydroxyalkyl cyclic diamine compound | KOWA CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| EP-1571144-A1 | HYDROXYALKYLATED CYCLIC DIAMINE COMPOUND | Kowa Co., Ltd. (JP) | 2005-09-07 | — | — | EP | disclosed |
| US-20040176593-A1 | Hydroxyalkyl cyclic diamine compound | KOWA CO., LTD. (JP) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176593-A1 | Hydroxyalkyl cyclic diamine compound | DDC, AOC1, ODC1 | L3MBTL1 4845/4885TSHR 4104/4885ALDH1A1 45/4885 |
| US-20070088159-A1 | HYDROXYALKYL CYCLIC DIAMINE COMPOUNDS | HDHD5, DDC, DDT | L3MBTL1 4724/4885TSHR 4300/4885ALDH1A1 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.