Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CASP4 | P49662 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.39 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4520072 | 0.93 | MAT2A (0.38) | CTSVCTSLCTSBCTSHCTSS | |
| SCHEMBL4522496 | 0.88 | CDK1 (0.39) | CTSVCTSLCTSBCTSHCTSS | |
| SCHEMBL4524676 | 0.87 | GAA (0.43) | SMN1; SMN2HKDC1CDK1TSHRLMNA | |
| SCHEMBL4524598 | 0.87 | RXFP1 (0.40) | CTSLSMN1; SMN2HKDC1CDK1LMNA | |
| SCHEMBL4529801 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2HKDC1CDK1NPC1RAB9A | |
| SCHEMBL4531589 | 0.85 | HKDC1 (0.39) | SMN1; SMN2HKDC1CDK1NPC1RAB9A | |
| SCHEMBL4521974 | 0.85 | SMN1; SMN2 (0.39) | CTSVCTSLCTSBCTSHCTSS | |
| SCHEMBL4517305 | 0.85 | MAOB (0.41) | SMN1; SMN2HKDC1CDK1MEN1KMT2A | |
| SCHEMBL4531196 | 0.84 | HKDC1 (0.39) | SMN1; SMN2HKDC1CDK1NPC1RAB9A | |
| SCHEMBL4521275 | 0.84 | ALDH1A3 (0.44) | CDK1HPGDMAT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298856-A1 | 2,3 Substituted fused bicyclic pyrimidin-4(3H)-ones modulating the function of the vanilliod-1receptor (VR1) | BROWN REBECCA ELIZABETH | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298856-A1 | 2,3 Substituted fused bicyclic pyrimidin-4(3H)-ones modulating the function of the vanilliod-1receptor (VR1) | TRPV1, TRPV2, TRPV4 | CTSV 3256/4885CTSL 4456/4885CTSB 3508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.