SCHEMBL4522152

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31128165	1.00	GRIN2D (0.41)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL8884172	0.85	GRIN2D (0.41)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL28720365	0.81	GRIN2D (0.40)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL28295982	0.81	MAPT (0.46)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL31128153	0.79	LMNA (0.45)	ALDH1A1MAPTHTTLMNATDP1
	SCHEMBL31128150	0.79	LMNA (0.45)	ALDH1A1MAPTHTTLMNATDP1
	SCHEMBL10394091	0.77	GRIN2D (0.37)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL23629187	0.70	MAPT (0.39)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
	SCHEMBL3211912	0.70	S1PR4 (0.41)	ALDH1A1MAPTHTTLMNANQO2
	SCHEMBL25037220	0.70	GPR35 (0.53)	ALDH1A1MAPTTDP1CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.