SCHEMBL45241

SCHEMBL45241

C=CC(O)C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.52
CES2 O00748 3/20 0.52
CES1 P23141 3/20 0.52
AKT1 P31749 1/20 0.50
TDP1 Q9NUW8 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
ALKBH5 Q6P6C2 1/20 0.44
MDM2 Q00987 1/20 0.44
ALDH1A1 P00352 5/20 0.42
TSHR P16473 2/20 0.42
DAO P14920 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
MAPK1 P28482 1/20 0.41
PGR P06401 1/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
HTR2A P28223 1/20 0.40
HRH1 P35367 1/20 0.40
KCNH2 Q12809 1/20 0.40
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mercaptopropionic Acid SCHEMBL20656577 0.85 ALKBH5 (0.41) LMNACES2CES1AKT1TDP1
SCHEMBL11287380 0.84 LMNA (0.54) LMNACES2CES1AKT1TDP1
SCHEMBL1720153 0.80 AKT1 (0.52) LMNACES2CES1AKT1TDP1
SCHEMBL1088403 0.80 CES2 (0.54) LMNACES2CES1AKT1TDP1
SCHEMBL27509839 0.78 LMNA (0.47) LMNACES2CES1AKT1TDP1
SCHEMBL26676884 0.78 LMNA (0.49) LMNACES2CES1AKT1TDP1
SCHEMBL45332 0.77 AKT1 (0.48) LMNACES2CES1AKT1TDP1
SCHEMBL9093296 0.77 LMNA (0.51) LMNACES2CES1AKT1TDP1
SCHEMBL6678865 0.77 AKT1 (0.48) LMNACES2CES1AKT1TDP1
SCHEMBL8978421 0.77 AKT1 (0.48) LMNACES2CES1AKT1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1099 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037424-B2 Enhanced, self-healable or recoverable and recyclable 3D printed article and preparation method and use thereof INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2024-07-16 US claimed
CN-118027756-A Ethylene-tetrafluoroethylene powder coating for anti-corrosion lining and preparation method thereof 山东东岳未来氢能材料股份有限公司 2024-05-14 CN claimed
CN-117377731-A Curable composition and use thereof 汉高股份有限及两合公司 2024-01-09 CN claimed
CN-117180112-A Adhesive for dentistry and application thereof 深圳爱尔创口腔技术有限公司 2023-12-08 CN claimed
CN-117017790-A Pit and groove sealing agent containing indicator, and preparation method and application thereof 辽宁爱尔创生物材料有限公司 2023-11-10 CN claimed
CN-116940647-A Curable adhesive composition comprising maleimide and thiol 汉高股份有限及两合公司 2023-10-24 CN claimed
CN-115943081-A Fast actinically curable composition for 3D composites 法国阿科玛 2023-04-07 CN claimed
CN-115895468-A Adhesive film for curved-surface image display device, preparation method of adhesive film and image display device 苏州凡赛特材料科技有限公司 2023-04-04 CN claimed
CN-113861854-B Adhesive film for image display device and image display device 苏州凡赛特材料科技有限公司 2023-03-31 CN claimed
CN-114074464-B Photochromic laminated glass, preparation method and application thereof 上海甘田光学材料有限公司 2022-12-16 CN claimed
US-20060052523-A1 Laminating adhesive, laminate including the same, and method of making a laminate H.B. FULLER CONSTRUCTION PRODUCTS INC. 2006-03-09 US claimed
CN-1644591-A Preparation of molecular weight gradient polymer UNIV BEIJING CHEMICAL (CN) 2005-07-27 CN claimed
CN-1622862-A Method for producing strongly adherent coatings CIBA SC HOLDING AG (CH) 2005-06-01 CN claimed
US-20050107486-A1 UV-curable polyols BAYER MATERIALSCIENCE LLC 2005-05-19 US claimed
EP-1106627-B1 Novel phosphine oxide photoinitiator systems and curable compositions with low color CIBA SC HOLDING AG (CH) 2003-10-29 EP claimed
CN-1437639-A Optical fiber coating composition DSM NV (NL) 2003-08-20 CN claimed
EP-1252240-A1 OPTICAL FIBER COATING COMPOSITION DSM N.V. (NL) 2002-10-30 EP claimed
US-20020099110-A1 RADIATION-CURABLE COATING COMPOSITION DSM N.V. (NL) 2002-07-25 US claimed
WO-2001049792-A1 OPTICAL FIBER COATING COMPOSITION DSM N.V. (NL) 2001-07-12 WO claimed
EP-1106627-A1 Novel phosphine oxide photoinitiator systems and curable compositions with low color Ciba SC Holding AG (CH) 2001-06-13 EP claimed