Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.55 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.55 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.55 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516777 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL23417641 | 0.78 | SMN1; SMN2 (0.84) | ALDH1A1KMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL4511567 | 0.78 | L3MBTL1 (0.49) | ALDH1A1KMT2ASMN1; SMN2HPGDMAPT | |
| SCHEMBL4526020 | 0.77 | L3MBTL1 (0.58) | ALDH1A1SMN1; SMN2HPGDPLAAT3PLAAT5 | |
| SCHEMBL17117265 | 0.76 | HPGD (0.61) | ALDH1A1SMN1; SMN2HPGDMAPTTAAR1 | |
| SCHEMBL4525519 | 0.76 | ALDH1A1 (0.72) | ALDH1A1KMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL14241870 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL80581 | 0.74 | ALDH1A1 (0.67) | ALDH1A1KMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL31370008 | 0.74 | ALDH1A1 (0.67) | ALDH1A1KMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL19438778 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1KMT2ASMN1; SMN2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221653-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | disclosed |
| EP-1937656-A1 | 7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS BETA 2 ADRENOCEPTOR AGONISTS | AstraZeneca AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007027134-A1 | 7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS β2 ADRENOCEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221653-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ADRB2, ADRB1, ADRA2C | ALDH1A1 243/4885KMT2A 1651/4885SMN1; SMN2 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.