Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4525007 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL4515486 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL4525011 | 0.76 | ALDH1A1 (0.43) | KDM4EALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL13674506 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL4510846 | 0.71 | L3MBTL1 (0.52) | KDM4EALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL4505471 | 0.69 | P2RX7 (0.49) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL4501886 | 0.69 | TNKS (0.46) | KDM4EALDH1A1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL4509814 | 0.68 | SIGMAR1 (0.44) | ALDH1A1KMT2AMEN1ATM | |
| SCHEMBL13674400 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL14177662 | 0.68 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBKMT2AMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | KDM4E 2703/4885ALDH1A1 51/4885TDP1 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.