Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4513449 | 0.84 | ALDH1A1 (0.44) | KMT2AALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL4535829 | 0.80 | CYP1A2 (0.45) | MAPTALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4511972 | 0.78 | SIGMAR1 (0.45) | MAPTALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL4535886 | 0.76 | CHRNB2 (0.56) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3207648 | 0.76 | KMT2A (0.67) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL15145789 | 0.75 | MEN1 (0.58) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31135773 | 0.75 | SMN1; SMN2 (0.64) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL2341651 | 0.75 | KMT2A (0.73) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL3222110 | 0.75 | SMN1; SMN2 (0.64) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL30760336 | 0.74 | ALDH1A1 (0.46) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | PLE PATRICK | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | AQP3, AQP1, F12 | MEN1 763/4885KMT2A 2980/4885MAPT 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.