SCHEMBL452806

SCHEMBL452806

O=C(CCc1ccc(O)cc1)Cc1ccc(O)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
CA2 P00918 3/20 0.56
CAMK2A Q9UQM7 1/20 0.56
ESR1 P03372 2/20 0.54
ESR2 Q92731 1/20 0.54
KDM4E B2RXH2 3/20 0.52
CYP19A1 P11511 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP2C19 P33261 2/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
MEN1 O00255 1/20 0.52
SLC16A3 O15427 1/20 0.52
LMNA P02545 1/20 0.52
TTR P02766 1/20 0.52
TP53 P04637 1/20 0.52
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
CYP3A4 P08684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154267 0.92 TDP1 (0.72) TDP1L3MBTL1CA2CAMK2ACYP19A1
SCHEMBL8108885 0.89 ESR1 (0.62) TDP1L3MBTL1CA2CAMK2AESR1
SCHEMBL13960328 0.88 TDP1 (0.66) TDP1L3MBTL1CA2CAMK2ACYP19A1
Letestuianin C SCHEMBL4410123 0.84 F2RL1 (0.60) TDP1L3MBTL1CA2ESR1ESR2
SCHEMBL7150590 0.84 CA2 (0.68) L3MBTL1CA2CAMK2AESR1ESR2
SCHEMBL107381 0.81 IAPP (0.65) TDP1CA2ESR1ESR2KDM4E
SCHEMBL11221142 0.81 L3MBTL1 (0.58) TDP1L3MBTL1HDAC2HDAC8MEN1
SCHEMBL106914 0.81 CA2 (0.54) TDP1L3MBTL1CA2CAMK2AESR1
SCHEMBL2028391 0.81 CA2 (0.65) TDP1L3MBTL1CA2CAMK2AESR1
SCHEMBL452362 0.80 TDP1 (0.79) TDP1L3MBTL1ALDH1A1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
US-11821047-B2 High pressure zone formation for pretreatment Apalta Patent OÜ (EE) 2023-11-21 US disclosed
US-20230295678-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2023-09-21 US disclosed
EP-4098750-A1 RAPID PRETREATMENT Sweetwater Energy, Inc. (US) 2022-12-07 EP disclosed
EP-3230463-B1 RAPID PRETREATMENT SWEETWATER ENERGY INC (US) 2022-05-25 EP disclosed
US-11332723-B2 Engineered microorganisms for production of commodity chemicals and cellular biomass THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-17 US disclosed
WO-2011028623-A2 MODIFIED ORGANISMS FOR IMPROVED SACCHARIFICATION OF BIOMASS QTEROS, INC. (US) 2011-03-10 WO disclosed
WO-2011008564-A2 COMPOSITIONS AND METHODS FOR IMPROVED SACCHARIFICATION OF BIOMASS QTEROS, INC. (US) 2011-01-20 WO disclosed
US-20100298611-A1 PRODUCTION OF FERMENTIVE END PRODUCTSFROM CLOSTRIDIUM sp. QTEROS, INC. (US) 2010-11-25 US disclosed
US-20100279354-A1 ADAPTING MICROORGANISMS FOR AGRICULTURAL PRODUCTS EVOLUGATE, LLC (US) 2010-11-04 US disclosed
US-20100268000-A1 Compositions and Methods for Fermentation of Biomass QTEROS, INC. (US) 2010-10-21 US disclosed
US-20100086981-A1 COMPOSITIONS AND METHODS FOR IMPROVED SACCHARIFICATION OF BIOMASS QTEROS, INC. (US) 2010-04-08 US disclosed
US-20090203089-A1 ISOLATED ALCOHOL DEHYDROGENASE ENZYMES AND USES THEREOF BIO ARCHITECTURE LAB, INC. (US) 2009-08-13 US disclosed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US disclosed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA TDP1 2746/4885L3MBTL1 4522/4885CA2 3146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.